Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860807 | 1.00 | DPP4 (0.56) | DPP4LMNAMAPK1CYP2D6SRC | |
| SCHEMBL939043 | 1.00 | DPP4 (0.56) | DPP4LMNAMAPK1CYP2D6SRC | |
| SCHEMBL4073511 | 1.00 | DPP4 (0.56) | DPP4LMNAMAPK1CYP2D6SRC | |
| SCHEMBL939042 | 1.00 | DPP4 (0.56) | DPP4LMNAMAPK1CYP2D6SRC | |
| SCHEMBL8058962 | 1.00 | DPP4 (0.56) | DPP4LMNAMAPK1CYP2D6SRC | |
| SCHEMBL6027457 | 0.98 | DPP4 (0.54) | DPP4LMNAMAPK1CYP2D6SRC | |
| Hydrochloric Acid SCHEMBL5860803 | 0.98 | DPP4 (0.54) | DPP4LMNAMAPK1CYP2D6SRC | |
| Hydrochloric Acid SCHEMBL8073692 | 0.98 | DPP4 (0.54) | DPP4LMNAMAPK1CYP2D6SRC | |
| Hydrochloric Acid SCHEMBL3184809 | 0.98 | DPP4 (0.54) | DPP4LMNAMAPK1CYP2D6SRC | |
| Cadaverine Tartrate SCHEMBL30110790 | 0.91 | DPP4 (0.64) | DPP4LMNAMAPK1CYP2D6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107188895-B | C-13 and C-14 site structure modified taxol compounds and preparation method thereof | 上海大学 | 2020-03-13 | — | — | CN | claimed |
| WO-2012118318-A2 | MICROORGANISM FOR PRODUCING NON-NATURAL AMINO ACIDS, AND METHOD FOR PRODUCING NON-NATRUAL AMINO ACIDS USING SAME | 이화여자대학교 산학협력단 (KR) | 2012-09-07 | — | — | WO | claimed |
| WO-2010059916-A2 | PREPARATION OF DOCETAXEL | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-05-27 | — | — | WO | claimed |
| EP-1961735-B1 | Process for the preparation of (2r,3s)-3-phenylisoserine methyl ester acetate salt | INDENA SPA (IT) | 2009-11-18 | — | — | EP | claimed |
| EP-0935596-B1 | METHOD FOR PACLITAXEL SYNTHESIS | NAPRO BIOTHERAPEUTICS INC (US) | 2005-02-02 | — | — | EP | claimed |
| EP-0603176-B2 | beta-PHENYLISOSERINE-(2R,3S), SALTS, PREPARATION AND USE THEREOF | AVENTIS PHARMA SA (FR) | 2003-06-18 | — | — | EP | claimed |
| EP-0837846-B1 | C-2' HYDROXYL-BENZYL PROTECTED, N-CARBAMATE PROTECTED (2R,3S)-3-PHENYLISOSERINE AND PRODUCTION PROCESS THEREFOR | NAPRO BIOTHERAPEUTICS INC (US) | 2001-11-07 | — | — | EP | claimed |
| EP-1049686-A1 | INTERMEDIATES AND METHODS USEFUL IN THE SEMISYNTHESIS OF PACLITAXEL AND ANALOGS | INDENA S.p.A. (IT) | 2000-11-08 | — | — | EP | claimed |
| EP-0935596-A4 | METHOD FOR PACLITAXEL SYNTHESIS | NAPRO BIOTHERAPEUTICS INC (US) | 1999-10-27 | — | — | EP | claimed |
| EP-0935596-A1 | METHOD FOR PACLITAXEL SYNTHESIS | NAPRO BIOTHERAPEUTICS, INC. (US) | 1999-08-18 | — | — | EP | claimed |
| US-5359124-A | Reacting benzylamine with cis-beta-phenylglycidic acid yields intermediate for anticarcinogenic taxol derivatives | AVENTIS PHARMA S.A. (FR) | 1994-10-25 | — | — | US | claimed |
| EP-0515540-B1 | DERIVATIVE OF BETA-PHENYLISOSERINE, PREPARATION AND UTILISATION THEREOF | RHONE POULENC RORER SA (FR) | 1994-07-06 | — | — | EP | claimed |
| EP-0603176-A1 | -g(b)-PHENYLISOSERINE-(2R,3S), SALTS, PREPARATION AND USE THEREOF. | RHONE POULENC RORER SA (FR) | 1994-06-29 | — | — | EP | claimed |
| US-5294737-A | Hydrolysis, cyclization, condensation | THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) | 1994-03-15 | — | — | US | claimed |
| EP-0336840-B1 | Process for the preparation of taxol | CENTRE NAT RECH SCIENT (FR) | 1993-11-18 | — | — | EP | claimed |
| EP-0603176-A4 | -g(b)-PHENYLISOSERINE-(2R,3S), SALTS, PREPARATION AND USE THEREOF. | RHONE POULENC RORER SA (FR) | 1993-09-17 | — | — | EP | claimed |
| EP-0515540-A1 | DERIVATIVE OF BETA-PHENYLISOSERINE, PREPARATION AND UTILISATION THEREOF. | RHONE POULENC RORER SA (FR) | 1992-12-02 | — | — | EP | claimed |
| WO-1992012958-A1 | β-PHENYLISOSERINE-(2R,3S), SALTS, PREPARATION AND USE THEREOF | RHONE-POULENC RORER S.A. (FR) | 1992-08-06 | — | — | WO | claimed |
| EP-0495718-A1 | Beta-phenylisoserine-(2R,3S), salts, preparation and use thereof | Aventis Pharma S.A. (FR) | 1992-07-22 | — | — | EP | claimed |
| WO-1991013053-A1 | DERIVATIVE OF β-PHENYLISOSERINE, PREPARATION AND UTILISATION THEREOF | RHONE-POULENC RORER S.A. (FR) | 1991-09-05 | — | — | WO | claimed |