Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4875267 | 0.89 | ALDH1A1 (0.79) | KMT2AMEN1ALDH1A1KDM4EKCNH2 | |
| SCHEMBL3074396 | 0.88 | MEN1 (0.68) | KMT2AMEN1ALDH1A1KDM4EKCNH2 | |
| SCHEMBL4874442 | 0.86 | POLB (0.71) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL27943670 | 0.85 | MEN1 (0.64) | KMT2AMEN1ALDH1A1KDM4EKCNH2 | |
| SCHEMBL3688168 | 0.85 | MEN1 (0.64) | KMT2AMEN1ALDH1A1KDM4EKCNH2 | |
| SCHEMBL28135954 | 0.85 | MEN1 (0.64) | KMT2AMEN1ALDH1A1KDM4EKCNH2 | |
| SCHEMBL10432577 | 0.85 | ALDH1A1 (0.70) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL21044195 | 0.84 | ALDH1A1 (0.72) | KMT2AMEN1ALDH1A1KCNH2MAPK1 | |
| SCHEMBL17549668 | 0.83 | KMT2A (0.84) | KMT2AMEN1ALDH1A1KCNH2SIGMAR1 | |
| SCHEMBL252026 | 0.83 | HPGD (0.79) | KMT2AMEN1ALDH1A1KDM4EKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326710-B2 | Aralkyl formyl-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2008-02-05 | — | — | US | claimed |
| US-20050153981-A1 | Aralkyl formly-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2005-07-14 | — | — | US | claimed |
| EP-1553092-A1 | ARALKYL FORMYL-ALKYL PIPERAZINE DERIVATIVES AND THEIR USES AS CEREBRAL NERVE PROTECTIVE AGENT | Shanghai Institute of Pharmaceutical Industry (CN) | 2005-07-13 | — | — | EP | claimed |
| US-7326710-B2 | Aralkyl formyl-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2008-02-05 | — | — | US | disclosed |
| US-20050153981-A1 | Aralkyl formly-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2005-07-14 | — | — | US | disclosed |
| EP-1553092-A1 | ARALKYL FORMYL-ALKYL PIPERAZINE DERIVATIVES AND THEIR USES AS CEREBRAL NERVE PROTECTIVE AGENT | Shanghai Institute of Pharmaceutical Industry (CN) | 2005-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153981-A1 | Aralkyl formly-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | GAP43, FABP7, AGK | KMT2A 3987/4885MEN1 4248/4885ALDH1A1 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.