Sugi Predict

Sugi Predict / Targets / AGK

AGK

Acylglycerol kinase, mitochondrial · Q53H12 · AGK on Sugi Atlas →

0 patent compounds predicted against AGK, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to AGK by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Mitochondrial Oxidation and Insulin Resistance in Burn Patients Treated With Fenofibrate PHASE2/PHASE3WITHDRAWN
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
The Effects of Coenzyme A Combined With Abiraterone on Patients With CRPC PHASE1/PHASE2UNKNOWN
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus) PHASE1/PHASE2NOT_YET_RECRUITING
Bempedoic Acid Therapy for Polycystic Kidney Disease PHASE2NOT_YET_RECRUITING
Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients PHASE2COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
The Effect of Lowered Physical Activity on Insulin Sensitivity and Lipid and Glucose Metabolism nanCOMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
Skeletal Muscle Mitochondrial Abnormalities and the Metabolic Syndrome in PAH nanCOMPLETED
McArdle Disease Treatment by Ketogenic Diet nanCOMPLETED
Nephroprotective Effects of Carnitine and (PDE5) Inhibitor Agent Against Contrast Media-induced Nephropathy (CMN) nanUNKNOWN
Effect of Short-Term Exercise Training on ATP Synthesis in Relatives of Type 2 Diabetic Humans nanCOMPLETED
Skeletal Muscle Diacylglycerol and Sphingolipids - Impact of Localization and Species on Insulin Resistance in Humans nanCOMPLETED
Effect of Age on Glucose and Lipid Metabolism nanCOMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease nanCOMPLETED
Dietary Ketosis: Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation nanCOMPLETED
Mitochondrial Substrate Utilization in the Diabetic Human Heart nanRECRUITING
Free Fatty Acid Induced Insulin Resistance nanCOMPLETED
Lifestyle Intervention in Preparation for Pregnancy (LIPP) nanCOMPLETED
OEA for Targeting Lipid Metabolism in GWI nanCOMPLETED
Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Early Mobilization and Intensive Rehabilitation in the Critically Ill nanUNKNOWN
Cardiac Mitochondrial Function in Explanted Human Hearts nanUNKNOWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Reactive Oxygen Species Following Aortic Valve Replacement nanCOMPLETED
Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and Senescence nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a AGK binder may also engage these)

ProteinNameSimilarity
Q5RED7 — 1.000 Q5RED7 →
Q9ESW4 — 0.996 Q9ESW4 →
Q7ZYJ3 — 0.963 Q7ZYJ3 →
Q969V5 — 0.948 Q969V5 →
Q8K4Q7 — 0.947 Q8K4Q7 →
HELZ Probable helicase with zinc finger domain 0.947 landscape →
P48507 — 0.946 P48507 →
Q4G0N4 — 0.946 Q4G0N4 →
Q8VCM5 — 0.945 Q8VCM5 →
Q4R7G8 — 0.944 Q4R7G8 →
Q9UJG1 — 0.944 Q9UJG1 →
Q96JC1 — 0.944 Q96JC1 →
Q6NYU2 — 0.944 Q6NYU2 →
Q5RCC7 — 0.944 Q5RCC7 →
Q6DFV5 — 0.944 Q6DFV5 →
P48508 — 0.943 P48508 →
Q28C34 — 0.943 Q28C34 →
Q1HCL7 — 0.943 Q1HCL7 →
Q6P4H8 — 0.943 Q6P4H8 →
Q3T0J1 — 0.943 Q3T0J1 →
Q5ZLS2 — 0.943 Q5ZLS2 →
Q96RR1 — 0.943 Q96RR1 →
Q2T9Y6 — 0.942 Q2T9Y6 →
Q2T9W7 — 0.942 Q2T9W7 →
Q6DC64 — 0.942 Q6DC64 →
Q6TV19 — 0.942 Q6TV19 →
MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 0.941 landscape →
Q8C0Q9 — 0.941 Q8C0Q9 →
Q5ZLS7 — 0.941 Q5ZLS7 →
Q8BFR2 — 0.941 Q8BFR2 →