SCHEMBL4874545

SCHEMBL4874545

CCC(O)[Si](C)(C)O[Si](O[Si](C)(C)C(O)CC)(O[Si](C)(C)C(O)CC)O[Si](C)(C)C(O)CC

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1130722 0.89 TSHR (0.36) TSHR
SCHEMBL3174068 0.85
SCHEMBL6911335 0.84 TSHR (0.33) TSHR
SCHEMBL15139393 0.74 TSHR (0.33) TSHR
SCHEMBL6664579 0.73
SCHEMBL3170166 0.72
SCHEMBL5161770 0.72
SCHEMBL2928415 0.72 TSHR (0.32) TSHR
SCHEMBL1130557 0.68 LMNA (0.31) TSHR
SCHEMBL1484279 0.68 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7354982-B2 Saccaride residue-functional organopolysiloxanes and method for the preparation thereof DOW CORNING TORAY SILICONE CO., LTD. (JP) 2008-04-08 US disclosed
US-7208561-B2 Saccharide residue-functional organopolysiloxanes and method for the preparation thereof DOW CORNING TORAY SILICONE, CO. LTD. (JP) 2007-04-24 US disclosed
EP-1446440-B1 SACCHARIDE RESIDUE-FUNCTIONAL ORGANOPOLYSILOXANES AND METHOD FOR THE PREPARATION THEREOF DOW CORNING TORAY CO LTD (JP) 2007-03-07 EP disclosed
US-20060183877-A1 Saccaride residue-functional organopolysiloxanes and method for the preparation thereof DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) 2006-08-17 US disclosed
US-20050038184-A1 Saccharide residue-functional corganopolysiloxanes and method for the preparation thereof DOW CORNING TORAY SILICONE CO. LTD. (JP) 2005-02-17 US disclosed
EP-1446440-A1 SACCHARIDE RESIDUE-FUNCTIONAL ORGANOPOLYSILOXANES AND METHOD FOR THE PREPARATION THEREOF Dow Corning Toray Co., Ltd. (JP) 2004-08-18 EP disclosed
WO-2003042283-A1 SACCHARIDE RESIDUE-FUNCTIONAL ORGANOPOLYSILOXANES AND METHOD FOR THE PREPARATION THEREOF DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-05-22 WO disclosed