SCHEMBL1130722

SCHEMBL1130722

CCC(O)[Si](C)(C)O[Si](C)(C)C(O)CC

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911335 0.89 TSHR (0.33) TSHR
SCHEMBL4874545 0.89 TSHR (0.33) TSHR
SCHEMBL3170166 0.81
SCHEMBL15139393 0.78 TSHR (0.33) TSHR
SCHEMBL1130557 0.78 LMNA (0.31) TSHR
SCHEMBL6664579 0.78
SCHEMBL3174068 0.76
SCHEMBL5161770 0.76
SCHEMBL2928415 0.76 TSHR (0.32) TSHR
SCHEMBL1484279 0.72 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12116442-B2 Method for producing silicone hydrogel contact lenses ALCON INC. (CH) 2024-10-15 US claimed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
US-20210347929-A1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2021-11-11 US claimed
US-9822326-B2 Low viscosity, low volatility lubricating oil basestocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-11-21 US claimed
US-20150275127-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-01 US claimed
US-8808732-B2 Film forming personal care compositions and methods SHAOSHENG DONG (US) 2014-08-19 US claimed
US-20130058880-A1 FILM FORMING PERSONAL CARE COMPOSITIONS AND METHODS DONG SHAOSHENG (US) 2013-03-07 US claimed
US-8039049-B2 Treatment of low dielectric constant films using a batch processing system TOKYO ELECTRON LIMITED (JP) 2011-10-18 US claimed
US-7405168-B2 Plural treatment step process for treating dielectric films TOKYO ELECTRON LIMITED (JP) 2008-07-29 US claimed
US-20080076262-A1 METHOD AND SYSTEM FOR TREATING A DIELECTRIC FILM TOKYO ELECTRON LIMITED (JP) 2008-03-27 US claimed
US-7345000-B2 Method and system for treating a dielectric film TOKYO ELECTRON LIMITED (JP) 2008-03-18 US claimed
US-20070077353-A1 Plasma-assisted vapor phase treatment of low dielectric constant films using a batch processing system TOKYO ELECTRON LIMITED (JP) 2007-04-05 US claimed
US-20070077781-A1 Plural treatment step process for treating dielectric films TOKYO ELECTRON LIMTED (JP) 2007-04-05 US claimed
US-20050215072-A1 Method and system for treating a dielectric film TOKYO ELECTRON LIMITED (JP) 2005-09-29 US claimed
US-12116442-B2 Method for producing silicone hydrogel contact lenses ALCON INC. (CH) 2024-10-15 US disclosed
US-11945895-B2 Photochromic polydiorganosiloxane vinylic crosslinkers ALCON INC. (CH) 2024-04-02 US disclosed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP disclosed
WO-1995029968-A1 LIGHT MODULATING DEVICE HAVING A MATRIX PREPARED FROM ACID REACTANTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-09 WO disclosed
WO-1995004791-A1 LIGHT MODULATING DEVICE HAVING A SILICON-CONTAINING MATRIX MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-16 WO disclosed
US-4689383-A Hydroxyl-functional disiloxanes and polysiloxane oligomers THORATEC LABORATORIES CORP. (US) 1987-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130058880-A1 FILM FORMING PERSONAL CARE COMPOSITIONS AND METHODS CUTA, PWWP2B, WIZ TSHR 4194/4885
US-20150275127-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS SBK1, BRSK1, BRSK2 TSHR 3982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.