SCHEMBL4874557

SCHEMBL4874557

CCN(CC)C1CCN(C(=O)Cn2c(-c3ccc4nc(-c5sc(C)nc5C)ccc4c3)c(-c3ccccc3)c3sc(C(=O)O)cc32)CC1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CBX7 O95931 2/20 0.38
CDYL2 Q8N8U2 2/20 0.38
CDYL Q9Y232 2/20 0.38
HRH3 Q9Y5N1 4/20 0.36
KCNH2 Q12809 3/20 0.36
CDY1; CDY1B Q9Y6F8 1/20 0.35
BRD4 O60885 2/20 0.33
CREBBP Q92793 1/20 0.33
PIK3CA P42336 2/20 0.32
MTOR P42345 2/20 0.32
MAP4K4 O95819 1/20 0.31
GRIN2B Q13224 2/20 0.31
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4875085 0.93 CBX7 (0.37) CBX7CDYL2CDYLHRH3CDY1; CDY1B
SCHEMBL4868321 0.92 KCNH2 (0.38) HRH3KCNH2BRD4CREBBPPIK3CA
SCHEMBL4877213 0.91 CBX7 (0.35) CBX7CDYL2CDYLHRH3KCNH2
SCHEMBL4878773 0.91 CBX7 (0.39) CBX7CDYL2CDYLHRH3CDY1; CDY1B
SCHEMBL4876223 0.90 GRIN2B (0.39) HRH3KCNH2BRD4CREBBPGRIN2B
SCHEMBL4876347 0.90 GRIN2B (0.39) HRH3KCNH2BRD4CREBBPGRIN2B
SCHEMBL3934917 0.90 GRIN2B (0.38) HRH3KCNH2GRIN2B
SCHEMBL4877286 0.89 POLB (0.41) CBX7CDYL2CDYLHRH3KCNH2
SCHEMBL4868402 0.89 CBX7 (0.42) CBX7CDYL2CDYLCDY1; CDY1BPIK3CA
SCHEMBL3938012 0.89 KCNH2 (0.35) HRH3KCNH2BRD4CREBBPGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080051384-A1 ANTIVIRAL AGENTS GENELABS TECHNOLOGIES, INC. 2008-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080051384-A1 ANTIVIRAL AGENTS EIF2AK2, MAVS, ZC3HAV1 CBX7 2500/4885CDYL2 4283/4885CDYL 4218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.