SCHEMBL4868402

SCHEMBL4868402

CCN(CC)C1CCN(C(=O)Cn2c(-c3ccc4nc(-c5ccc(F)cc5)ccc4c3)c(-c3ccccc3)c3sc(C(=O)O)cc32)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CBX7 O95931 2/20 0.42
CDYL2 Q8N8U2 2/20 0.42
CDYL Q9Y232 2/20 0.42
CDY1; CDY1B Q9Y6F8 1/20 0.42
ACKR3 P25106 1/20 0.36
ALDH1A1 P00352 2/20 0.36
PKM P14618 1/20 0.36
PIK3CA P42336 2/20 0.34
MTOR P42345 2/20 0.34
KDM4E B2RXH2 2/20 0.34
TRPC3 Q13507 1/20 0.33
TRPC7 Q9HCX4 1/20 0.33
ENPP2 Q13822 1/20 0.32
GRM5 P41594 1/20 0.32
GRIN2B Q13224 2/20 0.32
MAPT P10636 2/20 0.32
PRCP P42785 1/20 0.32
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4878773 0.94 CBX7 (0.39) CBX7CDYL2CDYLCDY1; CDY1BALDH1A1
SCHEMBL4879240 0.92 TDP1 (0.39) CBX7CDYL2CDYLCDY1; CDY1BALDH1A1
SCHEMBL4874557 0.89 CBX7 (0.38) CBX7CDYL2CDYLCDY1; CDY1BPIK3CA
SCHEMBL4875085 0.89 CBX7 (0.37) CBX7CDYL2CDYLCDY1; CDY1BPIK3CA
SCHEMBL4883873 0.89 CBX7 (0.38) CBX7CDYL2CDYLCDY1; CDY1BALDH1A1
SCHEMBL4867721 0.89 CBX7 (0.38) CBX7CDYL2CDYLCDY1; CDY1BPIK3CA
SCHEMBL4868392 0.89 CBX7 (0.40) CBX7CDYL2CDYLCDY1; CDY1BACKR3
SCHEMBL4877296 0.88 GAA (0.40) CBX7CDYL2CDYLCDY1; CDY1BALDH1A1
SCHEMBL4876431 0.85 GRM5 (0.34) ALDH1A1PKMKDM4EGRM5GRIN2B
SCHEMBL4877128 0.84 LMNA (0.36) ALDH1A1PIK3CAMTORKDM4EGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080051384-A1 ANTIVIRAL AGENTS GENELABS TECHNOLOGIES, INC. 2008-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080051384-A1 ANTIVIRAL AGENTS EIF2AK2, MAVS, ZC3HAV1 CBX7 2500/4885CDYL2 4283/4885CDYL 4218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.