Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.36 |
| ▸ | CNR1 | P21554 | 10/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607920 | 0.99 | CNR1 (0.34) | CNR2CNR1 | |
| SCHEMBL5607347 | 0.95 | CNR1 (0.33) | CNR2CNR1 | |
| SCHEMBL5548676 | 0.91 | CDK4 (0.31) | MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5552344 | 0.87 | SOAT1 (0.34) | — | |
| SCHEMBL5548512 | 0.86 | BRD4 (0.32) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3397237 | 0.85 | — | — | |
| SCHEMBL3425601 | 0.80 | SMN1; SMN2 (0.30) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1455223 | 0.80 | NPC1 (0.36) | MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3402757 | 0.79 | NR1H4 (0.31) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5608064 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915824-B1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2022-05-25 | — | — | EP | disclosed |
| EP-2915824-A1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | Lummus Novolen Technology Gmbh (DE) | 2015-09-09 | — | — | EP | disclosed |
| EP-1828266-B1 | SUPPORTED METALLOCENE CATALYST COMPOSITIONS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2015-07-22 | — | — | EP | disclosed |
| US-20080287286-A1 | Metallocene catalysts, their synthesis and their use for the polymerization of olefins | PACZKOWSKI NICOLA S | 2008-11-20 | — | — | US | disclosed |
| US-7285608-B2 | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-10-23 | — | — | US | disclosed |
| US-20070082806-A1 | Metallocene catalysts, their synthesis and their use for the polymerization of olefins | PACZKOWSKI NICOLA S | 2007-04-12 | — | — | US | disclosed |
| US-7169864-B2 | Loeading and heating a catalyst support with an alumoxane and further loading with a Group IVB metallocene and a second aluminoxane cocatalyst alone or in combination with a Lewis Acid or ionic compound; improved catalyst selectivity and polymerization efficiency | NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) | 2007-01-30 | — | — | US | disclosed |
| US-20060116490-A1 | Metallocene catalysts, their synthesis and their use for the polymerization of olefins | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2006-06-01 | — | — | US | disclosed |
| US-20050239979-A1 | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2005-10-27 | — | — | US | disclosed |