SCHEMBL5607347

SCHEMBL5607347

CCCC[Si](CCCC)(C1C(C)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21)C1C(C)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.33
CNR2 P34972 3/20 0.33
CDK4 P11802 1/20 0.30
CCND1 P24385 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5607920 0.97 CNR1 (0.34) CNR1CNR2
SCHEMBL4874583 0.95 CNR2 (0.36) CNR1CNR2
SCHEMBL5548676 0.93 CDK4 (0.31) CDK4CCND1
SCHEMBL5548512 0.88 BRD4 (0.32)
SCHEMBL3397237 0.87
SCHEMBL5552344 0.82 SOAT1 (0.34)
SCHEMBL3425601 0.82 SMN1; SMN2 (0.30)
SCHEMBL1455223 0.81 NPC1 (0.36)
SCHEMBL3402757 0.81 NR1H4 (0.31)
SCHEMBL2388282 0.79 NPC1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7285608-B2 Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-10-23 US disclosed
US-20050239979-A1 Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2005-10-27 US disclosed