Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.80 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772272 | 0.87 | ALDH1A1 (0.81) | ALDH1A1POLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL14232240 | 0.81 | ALDH1A1 (0.72) | ALDH1A1POLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL10642418 | 0.77 | ALDH1A1 (0.67) | ALDH1A1POLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL9772293 | 0.77 | ALDH1A1 (0.56) | ALDH1A1POLBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL7038437 | 0.75 | ALDH1A1 (0.46) | ALDH1A1POLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL2558791 | 0.75 | ALDH1A1 (0.63) | ALDH1A1POLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL9772325 | 0.75 | ALDH1A1 (0.61) | ALDH1A1POLBSMN1; SMN2MAPTKDM4E | |
| SCHEMBL9422551 | 0.72 | ALDH1A1 (0.59) | ALDH1A1POLBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL4882281 | 0.71 | ALDH1A1 (0.44) | ALDH1A1POLBLMNAMAPTKDM4E | |
| SCHEMBL2558341 | 0.70 | ALDH1A1 (0.57) | ALDH1A1POLBSMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080281105-A1 | Novel Quinolinium Salts and Derivatives | IMMUSOL INCORPORATED (US) | 2008-11-13 | — | — | US | disclosed |
| CN-101106992-A | Novel quinolinium salts and derivatives | IMMUSOL INC (US) | 2008-01-16 | — | — | CN | disclosed |
| EP-1841428-A1 | NOVEL QUINOLINIUM SALTS AND DERIVATIVES | Immusol Incorporated (US) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006078754-A1 | NOVEL QUINOLINIUM SALTS AND DERIVATIVES | IMMUSOL INCORPORATED (US) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080281105-A1 | Novel Quinolinium Salts and Derivatives | NQO2, MCL1, KRAS | ALDH1A1 3206/4885POLB 1589/4885SMN1; SMN2 4426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.