SCHEMBL14232240

SCHEMBL14232240

CCn1c(C)cc(C=O)c1C

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 15/20 0.72
MAPT P10636 9/20 0.53
NPC1 O15118 5/20 0.53
RAB9A P51151 5/20 0.53
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
KDM4E B2RXH2 5/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
HTT P42858 3/20 0.48
HPGD P15428 2/20 0.48
TP53 P04637 1/20 0.48
LMNA P02545 3/20 0.47
GAA P10253 1/20 0.44
MAPK1 P28482 1/20 0.44
RECQL P46063 1/20 0.44
NPSR1 Q6W5P4 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C19 P33261 1/20 0.42
MCL1 Q07820 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9772272 0.85 ALDH1A1 (0.81) ALDH1A1MAPTNPC1RAB9AMEN1
SCHEMBL4874761 0.81 ALDH1A1 (0.80) ALDH1A1MAPTNPC1RAB9AMEN1
SCHEMBL2558341 0.76 ALDH1A1 (0.57) ALDH1A1MAPTRAB9AKDM4ESMN1; SMN2
SCHEMBL10642418 0.76 ALDH1A1 (0.67) ALDH1A1MAPTNPC1RAB9AMEN1
SCHEMBL9401952 0.76 ALDH1A1 (0.57) ALDH1A1MAPTNPC1RAB9AMEN1
SCHEMBL2551654 0.75 ALDH1A1 (0.55) ALDH1A1MAPTRAB9AMEN1KMT2A
SCHEMBL13568567 0.74 ALDH1A1 (0.56) ALDH1A1MAPTNPC1RAB9AMEN1
SCHEMBL2558523 0.73 ALDH1A1 (0.54) ALDH1A1RAB9AKDM4ESMN1; SMN2HTT
SCHEMBL9772389 0.73 ALDH1A1 (0.54) ALDH1A1MAPTNPC1RAB9AMEN1
SCHEMBL2558791 0.73 ALDH1A1 (0.63) ALDH1A1MAPTKDM4ESMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023135536-A1 CORALLINE CERAMIC MATERIAL, SENSOR AND METHOD FOR OBTAINING SAID MATERIAL UNIVERSIDAD DE LOS ANDES (CO) 2023-07-20 WO claimed
WO-2026044253-A1 GENETICALLY ENCODED FLUORESCENT SENSORS FOR VISUALIZING POLYAMINE LEVELS, UPTAKE, AND DISTRIBUTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-02-26 WO disclosed
US-12504393-B2 Method and system for determining the progesterone-associated physiological state of lactating cows YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2025-12-23 US disclosed
US-20250367321-A1 COMPOSITIONS AND METHODS INVOLVING ADGRG6 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-12-04 US disclosed
EP-4593953-A1 INHIBITION OF LUTEINIZING HORMONE (LH) ACTION AS TREATMENT OF PERIMENOPAUSAL AND POSTMENOPAUSAL SYMPTOMS AND COMPLICATIONS Rigshospitalet (DK) 2025-08-06 EP disclosed
US-20250199007-A1 EXTRACELLULAR VESICLE BIOMARKERS FOR BLADDER CANCER TYMORA ANALYTICAL OPERATIONS, LLC (US) 2025-06-19 US disclosed
US-20250186520-A1 ONCOLYTIC VIRUS COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER HOPE CITY (US) 2025-06-12 US disclosed
CN-120030359-A Timing sequence prediction method and system based on visual algorithm 西北农林科技大学 2025-05-23 CN disclosed
US-20250064056-A1 CONTACT PHEROMONE-CONTAINING COMPOSITION FOR CONTROLLING THRIPS, KIT COMPOSITION FOR CONTROLLING THRIPS, AND METHOD OF CONTROLLING THRIPS BY USING SAME ANDONG NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2025-02-27 US disclosed
EP-2648500-B1 PHYTOPHTHORA RESISTANCE IN SWEET PEPPERS HM CLAUSE (FR) 2025-01-29 EP disclosed
US-20220362260-A1 METHODS OF TREATING LIPEDEMA INCLUDING AKR1C1 AS A THERAPEUTIC TARGET MAGI EUREGIO SCS (IT) 2022-11-17 US disclosed
US-20220339134-A1 VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS, ELOVANOID HYDROXYLATED DERIVATIVES, AND METHODS OF USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-10-27 US disclosed
EP-4025201-A1 VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS, ELOVANOID HYDROXYLATED DERIVATIVES, AND METHODS OF USE Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (US) 2022-07-13 EP disclosed
WO-2022140418-A1 VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS, ELOVANOID HYDROXYLATED DERIVATIVES, AND METHODS OF USE THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2022-06-30 WO disclosed
CN-114650814-A Very long chain polyunsaturated fatty acid, elongin-like hydroxylated derivatives and methods of use 路易斯安娜州立大学监测委员会,农业和机械学院 2022-06-21 CN disclosed
WO-2022093857-A1 ONCOLYTIC VIRUS COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER CITY OF HOPE (US) 2022-05-05 WO disclosed
WO-2022051819-A1 APPARATUS AND PROCESS FOR ELECTROMAGNETIC IMAGING EMvision Medical Devices Ltd (AU) 2022-03-17 WO disclosed
EP-3713423-B1 PROCEDURE FOR THE PRODUCTION OF A MULTIPLIER AND MODULATOR ADDITIVE OF THE RUMINAL MICROBIOTE BIOPREMIX TECH LLC (US) 2022-02-09 EP disclosed
CN-113930416-A Preparation method of biochar immobilized laccase based on compound modification of sodium hydroxide and ferroferric oxide crystals 南开大学 2022-01-14 CN disclosed
US-20120308588-A1 NEPRILYSIN INHIBITORS THERAVANCE, INC. (US) 2012-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120308588-A1 NEPRILYSIN INHIBITORS MME, REN, ACE ALDH1A1 2714/4885MAPT 527/4885NPC1 214/4885
US-20220339134-A1 VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS, ELOVANOID HYDROXYLATED DERIVATIVES, AND METHODS OF USE ELOVL3, ELOVL1, ALOX5 ALDH1A1 631/4885MAPT 4822/4885NPC1 449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.