Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CCR4 | P51679 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14029367 | 0.85 | KMT2A (0.46) | KMT2ACCR4TOP2ATSHRGAA | |
| SCHEMBL12087313 | 0.82 | TLR8 (0.51) | KMT2ACCR4TOP2ATSHRFGFR1 | |
| SCHEMBL22304462 | 0.82 | TOP2A (0.43) | KMT2ACCR4TOP2ATSHRFGFR1 | |
| SCHEMBL14065592 | 0.82 | CACNA2D1 (0.44) | KMT2ACCR4TOP2ATSHRFGFR1 | |
| SCHEMBL25809403 | 0.81 | KMT2A (0.51) | KMT2ALMNANR1I2AHRMAPT | |
| SCHEMBL24700672 | 0.79 | TOP2A (0.42) | KMT2ACCR4TOP2ATSHRAPAF1 | |
| SCHEMBL14047483 | 0.79 | ALDH1A1 (0.46) | KMT2ACCR4TOP2ATSHRGAA | |
| SCHEMBL14181384 | 0.79 | TP53 (0.47) | KMT2ACCR4TOP2ATSHRFGFR1 | |
| SCHEMBL2783761 | 0.79 | KMT2A (0.71) | KMT2ALMNANR1I2AHR | |
| SCHEMBL1704387 | 0.79 | GAA (0.44) | CCR4TOP2ATSHRAPAF1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080251758-A1 | Triazine Compounds Comprising Substituents Containing Amino Groups and Carboxyl Groups | EVONIK DEGUSSA GMBH (DE) | 2008-10-16 | — | — | US | disclosed |
| EP-1787989-A1 | Triazine derivatives containing amino and carboxylic acic group | Degussa GmbH (DE) | 2007-05-23 | — | — | EP | disclosed |
| US-4370443-A | QUATERNARY AMMONIUM POLYTRIAZINES, MORDANTS, FIXING AGENTS, CATIONIC SURFACTANTS | STERLING DRUG INC. (US) | 1983-01-25 | — | — | US | disclosed |
| US-4347352-A | REACTING CYANURIC CHLORIDE WITH A TERTIARY AMINE; FOR USE AS MORDANTS, SOFTENERS, SURFACTANTS | STERLING DRUG INC. (US) | 1982-08-31 | — | — | US | disclosed |
| US-4314001-A | FOR SOFTENING FIBERS; TRIAZINE QUATERNARY AMMONIUM POLYMERS | STERLING DRUG INC. (US) | 1982-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080251758-A1 | Triazine Compounds Comprising Substituents Containing Amino Groups and Carboxyl Groups | GTF3C5, BAZ2A, AADAC | KMT2A 1207/4885LMNA 4433/4885CCR4 521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.