Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14029367 | 0.81 | KMT2A (0.46) | GAATOP2ATSHRCACNA2D1TP53 | |
| SCHEMBL9118084 | 0.79 | SLC29A1 (0.44) | TLR8CA1CA2CA9KDM4E | |
| SCHEMBL22304462 | 0.79 | TOP2A (0.43) | GAATOP2ATSHRCACNA2D1TP53 | |
| SCHEMBL14065592 | 0.79 | CACNA2D1 (0.44) | GAATOP2ATSHRCACNA2D1TP53 | |
| SCHEMBL4874795 | 0.79 | KMT2A (0.57) | GAATOP2ATSHRCACNA2D1CCR4 | |
| SCHEMBL12087313 | 0.79 | TLR8 (0.51) | GAATOP2ATSHRCACNA2D1TP53 | |
| SCHEMBL6279465 | 0.77 | KCNH3 (0.50) | TSHRTLR8CA1CA2CA9 | |
| SCHEMBL24700672 | 0.76 | TOP2A (0.42) | GAATOP2ATSHRCACNA2D1TP53 | |
| SCHEMBL14047483 | 0.76 | ALDH1A1 (0.46) | GAATOP2ATSHRCACNA2D1CCR4 | |
| SCHEMBL14181384 | 0.76 | TP53 (0.47) | GAATOP2ATSHRCACNA2D1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1892240-B1 | Benzoisoindole derivative, pigment composition comprising the same and colored composition | TOYO INK MFG CO (JP) | 2012-04-18 | — | — | EP | disclosed |
| US-20080289541-A1 | Benzoisoindole derivative, pigment composition comprising the same and colored composition | TOYO INK MFG. CO., LTD. (JP) | 2008-11-27 | — | — | US | disclosed |
| EP-1892240-A1 | Benzoisoindole derivative, pigment composition comprising the same and colored composition | TOYO INK MFG. CO., LTD. (JP) | 2008-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080289541-A1 | Benzoisoindole derivative, pigment composition comprising the same and colored composition | TYR, BRI3BP, MITF | GAA 1199/4885TOP2A 1120/4885TSHR 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.