SCHEMBL4875279

SCHEMBL4875279

O=C(O)Oc1cc(Cl)c(OC(=O)O)c2c(OC(=O)O)cc(Cl)c(OC(=O)O)c12

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TPMT P51580 1/20 0.34
PLAU P00749 1/20 0.33
ALDH1A1 P00352 3/20 0.32
HPGD P15428 1/20 0.32
FABP7 O15540 1/20 0.31
FABP3 P05413 1/20 0.31
FABP5 Q01469 1/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
POLB P06746 2/20 0.30
ALOX15 P16050 1/20 0.30
TTR P02766 1/20 0.30
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30
ACLY P53396 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14778478 0.94 TPMT (0.33) TPMTPLAUALDH1A1HPGDFABP7
SCHEMBL9834984 0.81 ALDH1A1 (0.35) ALDH1A1HPGDFABP7FABP3FABP5
SCHEMBL7105783 0.76 FABP7 (0.47) ALDH1A1HPGDFABP7FABP3FABP5
SCHEMBL10447737 0.76 CA1 (0.43) TPMTPLAUALDH1A1HPGDTDP1
SCHEMBL6555952 0.75 ADORA3 (0.31)
SCHEMBL4865955 0.74 MAPK1 (0.36) TPMTALDH1A1FABP7FABP3FABP5
SCHEMBL5693517 0.72 TSHR (0.42) TPMTALDH1A1HPGDFABP7FABP3
SCHEMBL10872006 0.70 TNFSF11 (0.30) ALDH1A1TDP1KDM4EGAAPOLB
SCHEMBL17026756 0.69 LCK (0.36) TPMTHTTALOX15THRATHRB
SCHEMBL323191 0.69 TNFSF11 (0.39) TPMTALDH1A1HPGDTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2579275-B1 INSULATED ELECTRIC WIRE LS CABLE LTD (KR) 2020-04-08 EP disclosed
EP-2579275-A2 INSULATED ELECTRIC WIRE LS Cable Ltd. (KR) 2013-04-10 EP disclosed
US-20130068500-A1 INSULATED WIRE LS CABLE & SYSTEM LTD. (KR) 2013-03-21 US disclosed
US-7471360-B2 Liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2008-12-30 US disclosed
US-20070046870-A1 Liquid crystal display device KONICA MINOLTA OPTO, INC. 2007-03-01 US disclosed