SCHEMBL487563

SCHEMBL487563

COC(=O)C1OC1c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.67
EPHX1 P07099 3/20 0.56
POLB P06746 1/20 0.51
CYP2D6 P10635 1/20 0.48
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
ITGA4 P13612 1/20 0.47
SLC6A3 Q01959 3/20 0.47
SLC6A4 P31645 2/20 0.47
MEN1 O00255 1/20 0.46
TP53 P04637 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
HPGD P15428 1/20 0.46
CYP2C19 P33261 1/20 0.46
KMT2A Q03164 1/20 0.46
BACE1 P56817 1/20 0.44
ATM Q13315 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
SLC6A2 P23975 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10001744 1.00 TSHR (0.67) TSHREPHX1POLBCYP2D6ALDH1A1
SCHEMBL487564 1.00 TSHR (0.67) TSHREPHX1POLBCYP2D6ALDH1A1
SCHEMBL9543017 1.00 TSHR (0.67) TSHREPHX1POLBCYP2D6ALDH1A1
SCHEMBL6233713 1.00 TSHR (0.67) TSHREPHX1POLBCYP2D6ALDH1A1
SCHEMBL10001742 1.00 TSHR (0.67) TSHREPHX1POLBCYP2D6ALDH1A1
SCHEMBL1692429 1.00 TSHR (0.67) TSHREPHX1POLBCYP2D6ALDH1A1
SCHEMBL8168248 1.00 TSHR (0.67) TSHREPHX1POLBCYP2D6ALDH1A1
SCHEMBL16477739 0.90 EPHX1 (0.61) TSHREPHX1POLBCYP2D6ALDH1A1
SCHEMBL15446214 0.87 TSHR (0.53) TSHREPHX1POLBALDH1A1MAPT
SCHEMBL7902731 0.85 TSHR (0.54) TSHREPHX1ALDH1A1MAPTITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US claimed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP claimed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US claimed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP claimed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO claimed
WO-2007088442-A1 DRY ICE PRODUCTS AND METHOD OF MAKING SAME L'AIR LIQUIDE-SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (US) 2007-08-09 WO claimed
WO-2004087932-A2 ENZYMATIC RESOLUTION OF (±) METHYL TRANS-3-PHENYL GLYCIDATE SHASUN CHEMICALS AND DRUGS LIMITED (IN) 2004-10-14 WO claimed
WO-2025051797-A1 USE OF PERFUME TO DISPERSE A CATIONIC MIXTURE IN WATER KAO CORPORATION S.A. (ES) 2025-03-13 WO disclosed
EP-4520811-A1 USE OF PERFUME TO DISPERSE A CATIONIC MIXTURE IN WATER KAO CORPORATION, S.A. (ES) 2025-03-12 EP disclosed
US-20240277012-A1 DUPLICATE BEVERAGE WANG JIE (US) 2024-08-22 US disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
CN-115894890-A Selective functionalized modification method of primary alcohol compound 华南理工大学 2023-04-04 CN disclosed
EP-0540009-A1 Process for producing epoxides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-05 EP disclosed
WO-1993003838-A1 CHIRAL CATALYSTS, CATALYTIC OXIDATION AND DISPROPORTIONATION REACTIONS, AND METHODS OF PRODUCING EPOXYCHROMANS AND TAXOL RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-03-04 WO disclosed
EP-0153692-B1 METHOD FOR ISOMERIZATION A GLYCIDATE DERIVATIVE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-07-29 EP disclosed
US-5132433-A PROCESS FOR THE PREPARATION OF CLAUSENAMIDE AND NEOCLAUSENAMIDE, AND DERIVATIVES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 1992-07-21 US disclosed
EP-0414020-A2 Process for the preparation of clausenamide and neoclausenamide and their derivatives BAYER AG (DE) 1991-02-27 EP disclosed
US-4621150-A METAL PERHALATE OR SULFONATE OR COMPLEX; GLYCIDATE, 2-HYDROXY-3-BUTENOATE, EPOXIDE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-11-04 US disclosed
EP-0153692-A2 Method for isomerization a glycidate derivative SAGAMI CHEMICAL RESEARCH CENTER (JP) 1985-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 TSHR 3246/4885EPHX1 3026/4885POLB 4295/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 TSHR 3246/4885EPHX1 3026/4885POLB 4295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.