Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184003 | 0.89 | MEN1 (0.51) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL3183990 | 0.89 | MEN1 (0.51) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL3184255 | 0.84 | LMNA (0.51) | ALDH1A1L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL3184266 | 0.84 | LMNA (0.51) | ALDH1A1L3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL3198986 | 0.84 | KMT2A (0.59) | ALDH1A1KMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL3198975 | 0.84 | KMT2A (0.59) | ALDH1A1KMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL3193117 | 0.82 | L3MBTL1 (0.51) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL3193107 | 0.82 | L3MBTL1 (0.51) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL3199240 | 0.81 | TSHR (0.54) | ALDH1A1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL3199233 | 0.81 | TSHR (0.54) | ALDH1A1KMT2AMEN1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470797-B2 | Fused heterocyclic imido and amido compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-30 | — | — | US | disclosed |