SCHEMBL487617

SCHEMBL487617

CCc1ccc(CC)nc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.55
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
KDM4E B2RXH2 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
KMT2A Q03164 2/20 0.42
MAPT P10636 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40
PPARG P37231 2/20 0.38
POLB P06746 1/20 0.38
CYP3A4 P08684 1/20 0.38
RXRA P19793 1/20 0.38
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30398570 1.00 HRH3 (0.55) HRH3CYP1A2CYP2D6KDM4EL3MBTL1
SCHEMBL662973 0.89 HRH3 (0.50) HRH3CYP1A2CYP2D6KDM4EL3MBTL1
SCHEMBL20411974 0.87 HRH3 (0.45) HRH3CYP1A2CYP2D6KDM4EL3MBTL1
SCHEMBL5737703 0.86 HRH3 (0.43) HRH3CYP1A2CYP2D6KDM4EL3MBTL1
SCHEMBL27674580 0.85 HRH3 (0.60) HRH3CYP1A2CYP2D6KDM4EL3MBTL1
SCHEMBL4121733 0.84 HRH3 (0.42) HRH3CYP1A2CYP2D6KDM4EL3MBTL1
SCHEMBL12440631 0.84 HRH3 (0.42) HRH3CYP1A2CYP2D6KDM4EL3MBTL1
SCHEMBL2600004 0.84 HRH3 (0.50) HRH3CYP1A2CYP2D6KDM4EL3MBTL1
SCHEMBL662136 0.84 HRH3 (0.46) HRH3CYP1A2CYP2D6KDM4EL3MBTL1
SCHEMBL13401237 0.84 HRH3 (0.50) HRH3CYP1A2CYP2D6KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10044060-B1 Secondary batteries with improved electrolyte YOUNG EDGAR D (US) 2018-08-07 US claimed
US-9328126-B2 Norbornenylhydrocarbylene dihydrocarbylboranes and methods of making the same PROMERUS, LLC (US) 2016-05-03 US claimed
US-20150353582-A1 NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME PROMERUS, LLC (US) 2015-12-10 US claimed
WO-2014121008-A1 NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME PROMERUS, LLC (US) 2014-08-07 WO claimed
US-8106200-B2 Pyridine borane complexes BASF SE (DE) 2012-01-31 US claimed
US-20110207934-A1 PYRIDINE BORANE COMPLEXES BASF SE (DE) 2011-08-25 US claimed
EP-2066631-B1 PYRIDINE BORANE COMPLEXES BASF SE (DE) 2011-04-06 EP claimed
EP-2066631-A1 PYRIDINE BORANE COMPLEXES BASF SE (DE) 2009-06-10 EP claimed
WO-2008034886-A1 PYRIDINE BORANE COMPLEXES BASF SE (DE) 2008-03-27 WO claimed
EP-3667751-B1 PASSIVATION OF METAL HALIDE PEROVSKITES UNIV OXFORD INNOVATION LTD (GB) 2026-03-11 EP disclosed
US-12391813-B2 Layered body including inorganic substrate and polyamic acid cured product TOYOBO CO., LTD. (JP) 2025-08-19 US disclosed
US-12288825-B2 Photovoltaic device comprising a metal halide perovskite and a passivating agent OXFORD PHOTOVOLTAICS LIMITED (GB) 2025-04-29 US disclosed
US-20250019508-A1 LAYERED BODY INCLUDING INORGANIC SUBSTRATE AND POLYAMIC ACID CURED PRODUCT TOYOBO CO., LTD. (JP) 2025-01-16 US disclosed
US-12172409-B2 Laminate of inorganic substrate/polymer film layer with attached protective film, laminate stack, laminate storage method, and laminate transport method TOYOBO CO., LTD. (JP) 2024-12-24 US disclosed
WO-1986006386-A1 THERMOSETTABLE POLYSTYRYLPYRIDINE PREPOLYMER TERMINATED WITH ETHYLENICALLY UNSATURATED GROUPS AND CURED PRODUCTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1986-11-06 WO disclosed
US-4575542-A Thermosettable polystyrylpyridine prepolymer terminated with ethylenically unsaturated groups and cured products therefrom THE DOW CHEMICAL COMPANY (US) 1986-03-11 US disclosed
US-4473711-A CHROMIUM(III) ION EXCHANGED RESIN CATALYST UNION CARBIDE CORPORATION (US) 1984-09-25 US disclosed
US-4108185-A HYDROSOLUBLE POLYMER L'OREAL (FR) 1978-08-22 US disclosed
US-4042602-A Synthesis of dideoxyzearalane and related compounds IMC CHEMICAL GROUP, INC. (US) 1977-08-16 US disclosed
US-3979400-A OXIDATION OF A PYRIDINE REILLY TAR & CHEMICAL CORPORATION (US) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150353582-A1 NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME CYP8B1, BDKRB1, CYP1B1 HRH3 709/4885CYP1A2 68/4885CYP2D6 266/4885
US-20110207934-A1 PYRIDINE BORANE COMPLEXES NBAS, BRD8, PAXBP1 HRH3 1122/4885CYP1A2 2009/4885CYP2D6 1820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.