Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 17/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600537 | 0.84 | P2RY12 (0.61) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL5012431 | 0.80 | P2RY12 (0.54) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4736388 | 0.78 | P2RY12 (0.73) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL3586432 | 0.76 | P2RY12 (0.62) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4785763 | 0.76 | P2RY12 (0.70) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4874230 | 0.72 | P2RY12 (0.54) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4737004 | 0.71 | P2RY12 (0.75) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL5055303 | 0.70 | P2RY12 (0.44) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4356065 | 0.68 | ALDH1A1 (0.55) | P2RY12CYP3A4CYP2C9ALDH1A1CYP2C19 | |
| SCHEMBL4872894 | 0.68 | P2RY12 (0.56) | P2RY12CYP3A4CYP2C9CHRM2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312208-A1 | Pyridine Analogues | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312208-A1 | Pyridine Analogues | P2RY12, P2RY11, P2RY1 | P2RY12 1/4885CYP3A4 140/4885CYP2C9 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.