Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4869365 | 0.87 | KMT2A (0.70) | CYP3A4ALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL14544253 | 0.84 | CYP3A4 (0.66) | CYP3A4CYP2D6PORCNALDH1A1KMT2A | |
| SCHEMBL4869349 | 0.84 | CYP3A4 (0.68) | CYP3A4CYP2D6PORCNALDH1A1KDM4E | |
| SCHEMBL16197998 | 0.82 | PORCN (0.75) | CYP3A4CYP2D6PORCNALDH1A1KDM4E | |
| SCHEMBL16197934 | 0.78 | PORCN (1.00) | CYP3A4CYP2D6PORCNALDH1A1KMT2A | |
| SCHEMBL14112021 | 0.77 | KDM4E (0.77) | CYP3A4ALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL14544266 | 0.77 | KMT2A (0.62) | CYP3A4CYP2D6ALDH1A1KDM4EKMT2A | |
| SCHEMBL11555450 | 0.77 | CYP3A4 (0.60) | CYP3A4CYP2D6PORCNALDH1A1KMT2A | |
| SCHEMBL16197793 | 0.76 | PORCN (0.74) | CYP3A4CYP2D6PORCNALDH1A1KMT2A | |
| SCHEMBL16201303 | 0.76 | PORCN (0.78) | CYP3A4CYP2D6PORCNALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080166310-A1 | Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof | L'OREAL (FR) | 2008-07-10 | — | — | US | disclosed |
| US-20080166310-A1 | Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof | L'OREAL (FR) | 2008-07-10 | — | — | US | disclosed |
| US-20080166310-A1 | Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof | L'OREAL (FR) | 2008-07-10 | — | — | US | disclosed |
| US-20070092467-A1 | Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers | L'OREAL (FR) | 2007-04-26 | — | — | US | disclosed |
| US-20070092467-A1 | Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers | L'OREAL (FR) | 2007-04-26 | — | — | US | disclosed |
| US-20070092467-A1 | Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers | L'OREAL (FR) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092467-A1 | Oxyacetamide compounds useful for stimulating or inducing the growth and/or retarding the loss of keratin fibers | HPGD, KRT18, PTGS1 | CYP3A4 1728/4885CYP2D6 642/4885PORCN 959/4885 |
| US-20080166310-A1 | Administration of 2-oxyacetamide compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting the depigmentation and/or bleaching thereof | KRT18, TYR, CRYAA | CYP3A4 3483/4885CYP2D6 2386/4885PORCN 1930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.