Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 13/20 | 0.43 |
| ▸ | HTR2A | P28223 | 8/20 | 0.43 |
| ▸ | HTR2C | P28335 | 8/20 | 0.43 |
| ▸ | PNMT | P11086 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14091674 | 0.77 | HTR2C (0.50) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| Succinic Acid SCHEMBL3961950 | 0.72 | HTR2C (0.42) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| SCHEMBL3965690 | 0.72 | HTR2B (0.47) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| SCHEMBL4876661 | 0.71 | SLC6A4 (0.39) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| SCHEMBL3966494 | 0.71 | HTR2A (0.43) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| Succinic Acid SCHEMBL3969905 | 0.70 | HTR2A (0.39) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| SCHEMBL3961292 | 0.68 | HTR2A (0.46) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| SCHEMBL12361268 | 0.68 | HTR2C (0.48) | HTR2BHTR2AHTR2CPNMTADRA2A | |
| Succinic Acid SCHEMBL3964933 | 0.68 | TBXAS1 (0.44) | HTR2BHTR2AHTR2CTBXAS1 | |
| SCHEMBL2254517 | 0.68 | HTR2A (0.44) | HTR2BHTR2AHTR2CPNMTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926712-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007028131-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[d]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |