Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | SHBG | P04278 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.52 |
| ▸ | PGR | P06401 | 4/20 | 0.52 |
| ▸ | AR | P10275 | 4/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | SNCA | P37840 | 2/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.52 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.52 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907204 | 0.89 | PSEN1 (0.48) | CYP3A4LMNAMAPTTSHRSHBG | |
| SCHEMBL4885697 | 0.86 | CYP3A4 (0.52) | CYP3A4LMNAMAPTTSHRSHBG | |
| SCHEMBL3275157 | 0.83 | CYP3A4 (0.55) | CYP3A4LMNAMAPTTSHRSHBG | |
| SCHEMBL3747284 | 0.78 | CYP17A1 (0.54) | CYP3A4LMNAMAPTTSHRSHBG | |
| SCHEMBL4876809 | 0.76 | CYP3A4 (0.55) | CYP3A4LMNAMAPTTSHRSHBG | |
| SCHEMBL4895190 | 0.74 | SHBG (0.77) | CYP3A4LMNAMAPTTSHRSHBG | |
| SCHEMBL6393057 | 0.74 | HSD17B10 (0.55) | CYP3A4LMNAMAPTTSHRSHBG | |
| SCHEMBL4895186 | 0.74 | SHBG (0.77) | CYP3A4LMNAMAPTTSHRSHBG | |
| SCHEMBL18799945 | 0.74 | SHBG (0.77) | CYP3A4LMNAMAPTTSHRSHBG | |
| SCHEMBL4889469 | 0.74 | SHBG (0.65) | CYP3A4LMNAMAPTTSHRSHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194812-A1 | Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene- 17Alpha-Pregn-4-Ene-3-One-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-08-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194812-A1 | Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene- 17Alpha-Pregn-4-Ene-3-One-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process | CYP17A1, HSD17B7, HSD17B11 | CYP3A4 55/4885LMNA 1403/4885MAPT 4288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.