Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.61 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.61 |
| ▸ | HRH1 | P35367 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | HRH2 | P25021 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.61 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4879639 | 0.90 | CHRM2 (0.67) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL574530 | 0.90 | CHRM2 (0.67) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL222587 | 0.89 | CHRM2 (0.58) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| Hydrochloric Acid SCHEMBL4771342 | 0.89 | CHRM2 (0.66) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL725535 | 0.87 | CHRM2 (0.77) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL14709412 | 0.87 | CHRM2 (0.77) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL13175653 | 0.87 | CHRM2 (0.77) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL2853537 | 0.86 | CHRM2 (0.62) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL222314 | 0.86 | CHRM2 (0.62) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL222588 | 0.86 | CHRM2 (0.62) | CHRM2CHRM1CHRM3CHRM5HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838659-B1 | PROCESS FOR PREPARATION OF N,N-DIISOPROPYL-3-(2-HYDROXY-5-METHYLPHENYL)-3-PHENYLPROPYLAMINE | LEK PHARMACEUTICALS (SI) | 2015-07-15 | — | — | EP | disclosed |
| US-20080045602-A1 | Process for Preparation of 3-(2-Hydroxy-5Methylphenyl)-N, N-Disopropyl-3-Phenylpropylamine | LEK PHARMACEUTICALS, D.D. (SI) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045602-A1 | Process for Preparation of 3-(2-Hydroxy-5Methylphenyl)-N, N-Disopropyl-3-Phenylpropylamine | SLC6A3, PNMT, PIR | CHRM2 1306/4885CHRM1 1501/4885CHRM3 988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.