Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 14/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928018 | 0.93 | GRIN2B (0.42) | GRIN2B | |
| SCHEMBL4875207 | 0.93 | GRIN2B (0.33) | GRIN2BNPC1RAB9AMAPT | |
| SCHEMBL4876725 | 0.89 | KMT2A (0.41) | GRIN2BRAB9AMAPT | |
| SCHEMBL4875250 | 0.89 | KMT2A (0.41) | GRIN2BRAB9AMAPT | |
| SCHEMBL4877145 | 0.88 | GRIN2B (0.37) | GRIN2BNPC1RAB9AMAPT | |
| SCHEMBL4870801 | 0.88 | CBX7 (0.39) | GRIN2B | |
| SCHEMBL4868713 | 0.88 | TDP1 (0.42) | GRIN2BNPC1RAB9AMAPT | |
| SCHEMBL4875677 | 0.86 | GRIN2B (0.34) | GRIN2BMAPT | |
| SCHEMBL4868740 | 0.85 | GRIN2B (0.41) | GRIN2BMAPT | |
| SCHEMBL4868467 | 0.85 | KDM4E (0.44) | GRIN2BNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | GRIN2B 3420/4885NPC1 679/4885RAB9A 1055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.