Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878029 | 0.90 | SMO (0.34) | SMOMAPTALDH1A1GAAKMT2A | |
| SCHEMBL4875667 | 0.89 | SMO (0.33) | GRIN2BGRM5SMOUBE2MDCUN1D1 | |
| SCHEMBL4877128 | 0.89 | LMNA (0.36) | GRIN2BGRM5SMOUBE2MDCUN1D1 | |
| SCHEMBL4876599 | 0.88 | DPP4 (0.33) | MAPTRXFP1MGLL | |
| SCHEMBL4877312 | 0.88 | PIK3CA (0.43) | SMOUBE2MDCUN1D1MAPTALDH1A1 | |
| SCHEMBL4877141 | 0.88 | LMNA (0.36) | SMOUBE2MDCUN1D1MAPTALDH1A1 | |
| SCHEMBL4866875 | 0.87 | ALDH1A1 (0.39) | MAPTALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL4872104 | 0.86 | KDM4E (0.40) | GRM5UBE2MDCUN1D1MAPTALDH1A1 | |
| SCHEMBL4868321 | 0.86 | KCNH2 (0.38) | GRIN2BGRM5SMOMTORPIK3CA | |
| SCHEMBL4878306 | 0.86 | PIK3CA (0.40) | GRM5SMOMAPTMTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | GRIN2B 3420/4885GRM5 4042/4885SMO 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.