Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.50 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.50 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4880538 | 0.85 | SOAT1 (0.50) | KMT2AALDH1A1CYP3A4CYP2C19MEN1 | |
| SCHEMBL4881130 | 0.80 | DRD2 (0.49) | KMT2AMMP2MMP13 | |
| SCHEMBL4877226 | 0.75 | SIGMAR1 (0.48) | KMT2AALDH1A1CYP3A4CYP2C19MEN1 | |
| Hydrochloric Acid SCHEMBL4880947 | 0.70 | SOAT1 (0.51) | KMT2AMEN1 | |
| SCHEMBL20789429 | 0.70 | KMT2A (0.67) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL3281993 | 0.70 | KMT2A (0.58) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL3087224 | 0.69 | KMT2A (0.61) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL2858838 | 0.69 | MEN1 (0.75) | KMT2AALDH1A1HDAC4MEN1USP2 | |
| SCHEMBL20491201 | 0.68 | NPSR1 (0.50) | KMT2AALDH1A1MLYCDCYP3A4MEN1 | |
| SCHEMBL27461501 | 0.67 | HDAC3 (0.52) | KMT2AALDH1A1CYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096922-A1 | Novel Sulfonamide derivative | NR4A1, NR4A2, NR4A3 | KMT2A 1132/4885TET3 2143/4885FBXL19 3690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.