SCHEMBL4877285

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4876782	0.93	GAA (0.37)	MAPTIRAK4TP53GAAPOLB
	SCHEMBL4878071	0.93	TP53 (0.35)	MAPTIRAK4TP53GAAPOLB
	SCHEMBL4877463	0.91	GAA (0.36)	MAPTIRAK4TP53GAAPOLB
	SCHEMBL4872058	0.89	GAA (0.40)	MAPTIRAK4TP53GAAPOLB
	SCHEMBL2996646	0.89	GAA (0.42)	IRAK4GAAPOLBTSHRCYP2D6
	SCHEMBL4876422	0.89	HRH1 (0.34)	GAACYP2D6HRH1ALDH1A1KMT2A
	SCHEMBL4874410	0.89	TRPV4 (0.38)	IRAK4GAAPOLBTSHRGRIN2B
	SCHEMBL4877296	0.89	GAA (0.40)	MAPTIRAK4TP53GAAPOLB
	SCHEMBL4872438	0.89	TSHR (0.37)	TP53GAAPOLBTSHRALDH1A1
	SCHEMBL4868392	0.89	CBX7 (0.40)	GAACYP2D6HRH1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.