Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5771434 | 1.00 | HTR6 (0.41) | HTR6SOAT1ADRB1ALDH1A1MTNR1A | |
| Hydrochloric Acid SCHEMBL4880495 | 0.99 | HTR6 (0.40) | HTR6SOAT1ADRB1ALDH1A1MTNR1A | |
| Hydrochloric Acid SCHEMBL4872697 | 0.99 | HTR6 (0.40) | HTR6SOAT1ADRB1ALDH1A1MTNR1A | |
| Hydrochloric Acid SCHEMBL4872712 | 0.99 | HTR6 (0.40) | HTR6SOAT1ADRB1ALDH1A1MTNR1A | |
| SCHEMBL14194845 | 0.92 | SOAT1 (0.42) | HTR6SOAT1ALDH1A1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL4870740 | 0.91 | SOAT1 (0.41) | HTR6SOAT1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL4877681 | 0.89 | SOAT1 (0.46) | HTR6SOAT1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL4877679 | 0.89 | SOAT1 (0.46) | HTR6SOAT1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL4878278 | 0.85 | SOAT1 (0.48) | SOAT1ALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL14194844 | 0.84 | HTR2C (0.39) | HTR6SOAT1ALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1736467-A1 | NOVEL SULFONAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |