SCHEMBL487784

SCHEMBL487784

CC(CCC(N)=O)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
KMT2A Q03164 1/20 0.46
DPP4 P27487 1/20 0.46
DPP8 Q6V1X1 1/20 0.46
DPP9 Q86TI2 1/20 0.46
CYP1A2 P05177 1/20 0.42
GABRP O00591 2/20 0.37
GABRD O14764 2/20 0.37
GABRA1 P14867 2/20 0.37
GABRB1 P18505 2/20 0.37
GABRG2 P18507 2/20 0.37
GABRB3 P28472 2/20 0.37
GABRA5 P31644 2/20 0.37
GABRA3 P34903 2/20 0.37
GABRA2 P47869 2/20 0.37
GABRB2 P47870 2/20 0.37
GABRA4 P48169 2/20 0.37
GABRE P78334 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14895150 1.00 ALOX15 (0.46) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL15774679 1.00 ALOX15 (0.46) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL11137912 0.87 LTA4H (0.41) ALOX15BLMPMP22KMT2ADPP4
Glycerin SCHEMBL8015455 0.87 DPP4 (0.39) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL1679787 0.85 LTA4H (0.48) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL8642580 0.84 TSHR (0.38) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL28107169 0.83 LTA4H (0.47) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL2904041 0.83 LTA4H (0.47) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL15156195 0.83 LTA4H (0.47) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL13176582 0.82 CYP1A2 (0.65) ALOX15BLMPMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115895248-B Nylon polyphenyl ether composite material and preparation method and application thereof 惠州市沃特新材料有限公司 2024-12-03 CN claimed
EP-1453789-A2 N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES Elan Pharmaceuticals, Inc. (US) 2004-09-08 EP claimed
WO-2003040096-A2 N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES ELAN PHARMACEUTICALS, INC. (US) 2003-05-15 WO claimed
CN-115895248-B Nylon polyphenyl ether composite material and preparation method and application thereof 惠州市沃特新材料有限公司 2024-12-03 CN disclosed
CN-118202241-A Model training device for inspection, inspection device, model training method for inspection, inspection method, program, recovery method, continuous fiber reinforced resin composite material, and manufacturing method 旭化成株式会社 2024-06-14 CN disclosed
CN-117178085-A air textured yarn 莱卡英国有限公司 2023-12-05 CN disclosed
US-11764321-B2 Backsheet comprising a polyolefine based functional layer facing the back encapsulant ENDURANCE SOLAR SOLUTIONS B.V. (NL) 2023-09-19 US disclosed
WO-2023116934-A1 KRASG12D PROTEIN HYDROLYSIS REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 苏州泽璟生物制药股份有限公司 2023-06-29 WO disclosed
CN-115335373-A Compound and use thereof 福宏治疗公司 2022-11-11 CN disclosed
WO-2021162493-A1 PROTEIN KINASE DEGRADATION INDUCING COMPOUND, AND USE THEREOF 보로노이 주식회사 2021-08-19 WO disclosed
CN-107075142-B Fiber-reinforced thermoplastic resin molded article and fiber-reinforced thermoplastic resin molding material 东丽株式会社 2021-03-16 CN disclosed
US-5936114-A Preparation of lactams from aliphatic α, ω-dinitriles E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-08-10 US disclosed
US-5922589-A ISOLATED COMAMONAS TESTOSTERONI 5-MGAM-4D WITH NITRILE HYDRATASE AND AMIDASE ACTIVITIES; FOR HIGH YIELD WITH HIGH REGIOSELECTIVITY AND BY PRODUCT INHIBITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-07-13 US disclosed
CN-1219167-A Preparation of Lactams from aliphatic alpha, omega-dinitriles DU PONT (US) 1999-06-09 CN disclosed
US-5908954-A CHEMICAL INTERMEDIATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-06-01 US disclosed
EP-0901468-A1 PREPARATION OF LACTAMS FROM ALIPHATIC $g(a),$g(v)-DINITRILES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-03-17 EP disclosed
US-5858736-A CONTACTING DINITRILE IN AQUEOUS MIXTURE WITH ENZYME CATALYST HAVING ALIPHATIC NITRILASE ACTIVITY OR COMBINATION OF NITRILE HYDRATASE AND AMIDASE ACTIVITY, CONTACTING PRODUCT WITH HYDROGEN AND HYDROGENATION CATALYST TO PRODUCE LACTAM E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-12 US disclosed
US-5814508-A TREATING A WHOLE CELL CATALYST TO SELECT FOR A REGIOSELECTIVE NITRILASE ACTIVITY OR A NITRILE HYDRATASE ACTIVITY; CATALYTIC CONVERSION OF ALPHA-OMEGA DINITRILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-09-29 US disclosed
US-5728556-A REGIOSELECTIVE NITRILE HYDRATASE CATALYSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-17 US disclosed
WO-1997044318-A1 PREPARATION OF LACTAMS FROM ALIPHATIC α,φ-DINITRILES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-11-27 WO disclosed