Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878047 | 1.00 | APP (0.62) | APPALDH1A1LMNANFE2L2KDM4E | |
| SCHEMBL8828421 | 0.91 | CYP3A4 (0.56) | APPALDH1A1LMNANFE2L2KDM4E | |
| SCHEMBL14148789 | 0.87 | L3MBTL1 (0.57) | APPSMN1; SMN2MAPTABCG2 | |
| SCHEMBL29407319 | 0.87 | L3MBTL1 (0.61) | APPALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL14148791 | 0.87 | L3MBTL1 (0.61) | APPALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL6166697 | 0.84 | CYP1A1 (0.58) | ALDH1A1LMNAKDM4EMAPK1CYP3A4 | |
| SCHEMBL6166690 | 0.84 | CYP1A1 (0.58) | ALDH1A1LMNAKDM4EMAPK1CYP3A4 | |
| SCHEMBL8828181 | 0.83 | CYP3A4 (0.52) | APPALDH1A1LMNAKDM4EMAPK1 | |
| SCHEMBL4410623 | 0.81 | CNR2 (0.69) | APPKDM4EACHE | |
| SCHEMBL4410626 | 0.81 | CNR2 (0.69) | APPKDM4EACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080038386-A1 | Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition | MOZA ASHOK K | 2008-02-14 | — | — | US | disclosed |