Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | SMO | Q99835 | 5/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872088 | 0.91 | KMT2A (0.36) | DHODHALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL4877132 | 0.90 | MAPT (0.35) | SMOALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL4878306 | 0.90 | PIK3CA (0.40) | PIK3CADHODHSMOEGFRCCNT1 | |
| SCHEMBL4866862 | 0.89 | KMT2A (0.36) | PIK3CAALDH1A1KMT2A | |
| SCHEMBL4878059 | 0.89 | KDM4E (0.38) | PIK3CADHODHCCNT1CDK9KCNH2 | |
| SCHEMBL4877302 | 0.89 | PIK3CA (0.39) | PIK3CASMOALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL4873748 | 0.87 | KMT2A (0.41) | DHODHALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL4877120 | 0.87 | ALDH1A1 (0.34) | SMOALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL4875238 | 0.87 | ALDH1A1 (0.39) | SMOALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL4876718 | 0.87 | ALDH1A1 (0.39) | SMOALDH1A1GAAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | PIK3CA 1299/4885DHODH 1087/4885SMO 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.