Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | FPR1 | P21462 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4879217 | 0.86 | ENPP2 (0.66) | CYP3A4CYP2C9MAPTHSD17B10MEN1 | |
| SCHEMBL29813896 | 0.84 | CYP3A4 (0.70) | CYP3A4CYP2C9CYP2D6MAPTTHRB | |
| SCHEMBL833831 | 0.82 | CYP3A4 (0.73) | CYP3A4CYP2C9CYP2D6MAPTTHRB | |
| SCHEMBL12316844 | 0.82 | ENPP2 (0.66) | MAPTHSD17B10KMT2ATSHRKDM4E | |
| SCHEMBL4882902 | 0.82 | MAPT (0.64) | CYP3A4CYP2C9CYP2D6MAPTTHRB | |
| SCHEMBL4880697 | 0.82 | HTT (0.61) | MEN1KMT2AGAAALDH1A1ENPP2 | |
| SCHEMBL29563681 | 0.80 | HTT (0.74) | CYP3A4CYP2C9CYP2D6MAPTTHRB | |
| SCHEMBL29583307 | 0.79 | KMT2A (0.69) | CYP3A4CYP2C9CYP2D6MAPTTHRB | |
| SCHEMBL29392969 | 0.79 | HTT (0.75) | CYP3A4CYP2C9CYP2D6MAPTTHRB | |
| SCHEMBL30101734 | 0.79 | HSD17B10 (0.69) | CYP3A4CYP2C9CYP2D6MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249154-A1 | Preventive and/or Therapeutic Agent For Disease In Which Mitochondrial Benzodiazephine Receptor Participates | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249154-A1 | Preventive and/or Therapeutic Agent For Disease In Which Mitochondrial Benzodiazephine Receptor Participates | MTNR1A, GSR, NLN | CYP3A4 927/4885CYP2C9 834/4885CYP2D6 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.