Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.40 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.40 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 5/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794538 | 0.81 | HPGDS (0.50) | FTOPIK3CDPIK3CBPIK3CGPIM1 | |
| SCHEMBL3928158 | 0.72 | PIK3CD (0.50) | PIK3CDPIK3CBPIK3CGPIM1GSK3B | |
| SCHEMBL3927169 | 0.69 | PIK3CD (0.43) | FTOPIK3CDPIK3CBPIK3CGPIM1 | |
| SCHEMBL4781461 | 0.68 | HPGDS (0.48) | PIK3CDPIK3CBPIK3CGPIM1GSK3B | |
| SCHEMBL3928764 | 0.68 | HPGDS (0.48) | PIK3CGPIP4K2APIP4K2BPIP4K2CHPGDS | |
| SCHEMBL4794592 | 0.67 | HPGDS (0.48) | FTOPIK3CDPIK3CBPIK3CGPIM1 | |
| SCHEMBL4794193 | 0.67 | HPGDS (0.52) | PIK3CDPIK3CBPIK3CGPIM1GSK3B | |
| SCHEMBL3928845 | 0.65 | HPGDS (0.57) | PIK3CDPIK3CBPIK3CGPIM1GSK3B | |
| SCHEMBL5830148 | 0.64 | PIK3CD (0.55) | PIK3CDPIK3CBPIK3CGPIP4K2APIP4K2B | |
| SCHEMBL22494027 | 0.64 | PIK3CD (0.55) | FTOPIK3CDPIK3CBPIK3CGPIP4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008059-A1 | ANTI-CANCER AGENTS ANS USES THEREOF | LOCUS PHARMACEUTICALS, INC. (US) | 2008-01-17 | — | — | WO | claimed |