SCHEMBL487874

SCHEMBL487874

BCCCCCCCC(CCCCC)CCCCC

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
FDPS P14324 4/20 0.43
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
DNM1 Q05193 2/20 0.42
OPRM1 P35372 1/20 0.40
GPR84 Q9NQS5 3/20 0.38
SPHK1 Q9NYA1 1/20 0.38
FFAR1 O14842 1/20 0.38
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7957865 0.87 LMNA (0.52) LMNAFDPSTSHRTHRBDNM1
SCHEMBL20746363 0.86 LMNA (0.68) LMNAFDPSTSHRTHRBDNM1
SCHEMBL20740310 0.86 LMNA (0.68) LMNAFDPSTSHRTHRBDNM1
SCHEMBL20746348 0.86 LMNA (0.68) LMNAFDPSTSHRTHRBDNM1
SCHEMBL20746409 0.86 LMNA (0.68) LMNAFDPSTSHRTHRBDNM1
SCHEMBL25125871 0.86 LMNA (0.68) LMNAFDPSTSHRTHRBDNM1
SCHEMBL20746400 0.86 LMNA (0.68) LMNAFDPSTSHRTHRBDNM1
SCHEMBL21996120 0.86 LMNA (0.68) LMNAFDPSTSHRTHRBDNM1
SCHEMBL20746187 0.86 LMNA (0.68) LMNAFDPSTSHRTHRBDNM1
SCHEMBL20746351 0.86 LMNA (0.68) LMNAFDPSTSHRTHRBDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8106200-B2 Pyridine borane complexes BASF SE (DE) 2012-01-31 US disclosed
US-20110207934-A1 PYRIDINE BORANE COMPLEXES BASF SE (DE) 2011-08-25 US disclosed
EP-2066631-B1 PYRIDINE BORANE COMPLEXES BASF SE (DE) 2011-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110207934-A1 PYRIDINE BORANE COMPLEXES NBAS, BRD8, PAXBP1 LMNA 3308/4885FDPS 121/4885TSHR 3483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.