Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859832 | 0.98 | LMNA (0.57) | TDP1LMNAEGFRCES2CES1 | |
| SCHEMBL28297913 | 0.90 | TDP1 (0.65) | TDP1LMNAEGFRCES2CES1 | |
| SCHEMBL28702570 | 0.90 | TDP1 (0.65) | TDP1LMNAEGFRCES2CES1 | |
| SCHEMBL27498332 | 0.90 | TDP1 (0.65) | TDP1LMNAEGFRCES2CES1 | |
| SCHEMBL30225789 | 0.90 | TDP1 (0.65) | TDP1LMNAEGFRCES2CES1 | |
| SCHEMBL30439792 | 0.90 | TDP1 (0.65) | TDP1LMNAEGFRCES2CES1 | |
| SCHEMBL10899485 | 0.88 | TDP1 (0.63) | TDP1LMNAEGFRCES2CES1 | |
| SCHEMBL30439628 | 0.88 | LMNA (0.64) | TDP1LMNAEGFRCES2CES1 | |
| SCHEMBL9311704 | 0.86 | TDP1 (0.61) | TDP1LMNAEGFRCES2CES1 | |
| SCHEMBL10899476 | 0.86 | TDP1 (0.61) | TDP1LMNAEGFRCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269440-A1 | Polymerization of Olefins | UNIVERSITY OF MASSACHUSETTS | 2008-10-30 | — | — | US | disclosed |
| WO-2006074211-A1 | POLYMERIZATION OF OLEFINS | UNIVERSITY OF MASSACHUSETTS (US) | 2006-07-13 | — | — | WO | disclosed |