Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28035644 | 0.86 | AKR1B1 (0.39) | TDP1MEN1KMT2AALDH1A1FFAR1 | |
| SCHEMBL410406 | 0.81 | MEN1 (0.38) | TDP1MEN1KMT2AALDH1A1ELANE | |
| SCHEMBL2467542 | 0.80 | LDHA (0.40) | TDP1MEN1KMT2AALDH1A1LDHA | |
| SCHEMBL1304727 | 0.78 | LDHA (0.38) | TDP1MEN1KMT2AALDH1A1LDHA | |
| SCHEMBL8897022 | 0.77 | TDP1 (0.37) | TDP1MEN1KMT2AALDH1A1FFAR3 | |
| SCHEMBL19318349 | 0.76 | TDP1 (0.48) | TDP1MEN1KMT2AFFAR3HDAC3 | |
| SCHEMBL28946097 | 0.75 | CES1 (0.41) | TDP1MEN1KMT2AALDH1A1FFAR3 | |
| SCHEMBL11356460 | 0.74 | LDHA (0.35) | TDP1MEN1KMT2AALDH1A1LDHA | |
| SCHEMBL21938427 | 0.74 | MEN1 (0.37) | TDP1MEN1KMT2AALDH1A1ELANE | |
| SCHEMBL23056882 | 0.74 | GPR84 (0.56) | TDP1MEN1KMT2AALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524917-B2 | 6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity | ALLERGAN, INC. (US) | 2013-09-03 | — | — | US | disclosed |
| US-20080171772-A1 | e.g. Methyl 1-Benzyl-6-methoxy-1H-indole-2-carboxylate; glaucoma, dry eye, angiogenesis, cardiovascular conditions and diseases, wound healing, platelet aggregation and thrombosis | ALLERGAN, INC. | 2008-07-17 | — | — | US | disclosed |
| WO-2007034997-A2 | FLUORESCENT LAMP | SHOWA DENKO K.K. (JP) | 2007-03-29 | — | — | WO | disclosed |
| WO-2007013640-A1 | Y2O3 FILM AND PROCESS FOR PRODUCING THE SAME | SHOWA DENKO K.K. (JP) | 2007-02-01 | — | — | WO | disclosed |
| EP-1326607-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING OXAPENEM-3-CARBOXILIC ACIDS | Amura Limited (GB) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032423-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING OXAPENEM-3-CARBOXYLIC ACIDS | AMURA LIMITED (GB) | 2002-04-25 | — | — | WO | disclosed |
| EP-0125253-A1 | A PROCESS FOR THE PREPARATION OF 3-HYDROXY-ISOXAZOLOLE | A/S CHEMINOVA (DK) | 1984-11-21 | — | — | EP | disclosed |
| WO-1984001774-A1 | A PROCESS FOR THE PREPARATION OF 3-HYDROXY-ISOXAZOLOLE | CHEMINOVA AS (DK) | 1984-05-10 | — | — | WO | disclosed |
| US-3993637-A | Chelatable triazolylazo-N-alkyl(cycloalkyl)acylacetamide dyes | EASTMAN KODAK COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171772-A1 | e.g. Methyl 1-Benzyl-6-methoxy-1H-indole-2-carboxylate; glaucoma, dry eye, angiogenesis, cardiovascular conditions and diseases, wound healing, platelet aggregation and thrombosis | PTGIR, S1PR1, TBXA2R | TDP1 512/4885MEN1 2449/4885KMT2A 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.