Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460018 | 0.89 | TSHR (0.35) | CA2MAPK1TSHR | |
| SCHEMBL392423 | 0.83 | HSP90AA1 (0.32) | CA2MAPK1MAPT | |
| SCHEMBL8462087 | 0.82 | GAA (0.31) | TDP1ALDH1A1TSHR | |
| SCHEMBL17433678 | 0.80 | CA2 (0.37) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL28022756 | 0.80 | CHRM1 (0.48) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL8463312 | 0.78 | — | — | |
| SCHEMBL28022722 | 0.78 | GPR84 (0.53) | CA2MAPK1GPR84SLC1A2SLC1A1 | |
| SCHEMBL28023367 | 0.78 | GPR84 (0.53) | CA2MAPK1GPR84SLC1A2SLC1A1 | |
| SCHEMBL6310238 | 0.77 | TDP1 (0.42) | CHRM1ADRA1ATDP1GRIK1MAPT | |
| SCHEMBL993239 | 0.77 | CHRM1 (0.33) | CA2MAPK1CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104755510-A | Ziegler-Natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same | INDIAN OIL CORP LTD | 2015-07-01 | — | — | CN | claimed |
| CN-104755510-A | Ziegler-Natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same | INDIAN OIL CORP LTD | 2015-07-01 | — | — | CN | disclosed |
| US-8524917-B2 | 6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity | ALLERGAN, INC. (US) | 2013-09-03 | — | — | US | disclosed |
| US-20080171772-A1 | e.g. Methyl 1-Benzyl-6-methoxy-1H-indole-2-carboxylate; glaucoma, dry eye, angiogenesis, cardiovascular conditions and diseases, wound healing, platelet aggregation and thrombosis | ALLERGAN, INC. | 2008-07-17 | — | — | US | disclosed |
| WO-2007034997-A2 | FLUORESCENT LAMP | SHOWA DENKO K.K. (JP) | 2007-03-29 | — | — | WO | disclosed |
| WO-2007013640-A1 | Y2O3 FILM AND PROCESS FOR PRODUCING THE SAME | SHOWA DENKO K.K. (JP) | 2007-02-01 | — | — | WO | disclosed |
| EP-0125253-A1 | A PROCESS FOR THE PREPARATION OF 3-HYDROXY-ISOXAZOLOLE | A/S CHEMINOVA (DK) | 1984-11-21 | — | — | EP | disclosed |
| WO-1984001774-A1 | A PROCESS FOR THE PREPARATION OF 3-HYDROXY-ISOXAZOLOLE | CHEMINOVA AS (DK) | 1984-05-10 | — | — | WO | disclosed |
| US-4289847-A | 2-EQUIVALENT YELLOW COUPLER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1981-09-15 | — | — | US | disclosed |
| US-3993637-A | Chelatable triazolylazo-N-alkyl(cycloalkyl)acylacetamide dyes | EASTMAN KODAK COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171772-A1 | e.g. Methyl 1-Benzyl-6-methoxy-1H-indole-2-carboxylate; glaucoma, dry eye, angiogenesis, cardiovascular conditions and diseases, wound healing, platelet aggregation and thrombosis | PTGIR, S1PR1, TBXA2R | CA2 2089/4885MAPK1 1396/4885CHRM1 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.