Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245148 | 0.80 | ALDH1A1 (0.48) | TSHRCA2CA4CA5AALDH1A1 | |
| SCHEMBL2486283 | 0.77 | ALDH1A1 (0.55) | TSHRCA2CA4CA5AALDH1A1 | |
| SCHEMBL18037933 | 0.76 | CA2 (0.54) | TSHRCA2CA4CA5AALDH1A1 | |
| SCHEMBL11228761 | 0.75 | TSHR (0.54) | TSHRCA2CA4CA5AALDH1A1 | |
| SCHEMBL6150967 | 0.75 | TSHR (0.54) | TSHRCA2CA4CA5AALDH1A1 | |
| SCHEMBL4924733 | 0.73 | TSHR (0.52) | TSHRCA2CA4CA5AALDH1A1 | |
| SCHEMBL13010426 | 0.73 | TSHR (0.52) | TSHRCA2CA4CA5AALDH1A1 | |
| SCHEMBL15711851 | 0.73 | TSHR (0.52) | TSHRCA2CA4CA5AALDH1A1 | |
| SCHEMBL17488912 | 0.73 | TSHR (0.47) | TSHRCA2CA4CA5AALDH1A1 | |
| SCHEMBL19353458 | 0.72 | CA2 (0.62) | TSHRCA2CA4CA5AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028216-A | Asymmetric syntheses and intermediates for preparing enantiomer-enriched hydroxyphosphinyl derivatives | GUILFORD PHARMACEUTICALS INC. (US) | 2000-02-22 | — | — | US | claimed |
| WO-1999033848-B1 | PROCESS FOR PREPARING ENANTIOMER-ENRICHED HYDROXYPHOSPHINYL DERIVATIVES | GUILFORD PHARM INC (US) | 1999-08-12 | — | — | WO | claimed |
| WO-1999033848-A1 | PROCESS FOR PREPARING ENANTIOMER-ENRICHED HYDROXYPHOSPHINYL DERIVATIVES | GUILFORD PHARMACEUTICALS INC. (US) | 1999-07-08 | — | — | WO | claimed |
| CN-106165175-B | High molecular electrolyte composition and polyelectrolyte membrane, film electrode composite element and the polymer electrolyte fuel cell for using it | 东丽株式会社 | 2019-11-08 | — | — | CN | disclosed |
| US-10103401-B2 | Polymer electrolyte composition and polymer electrolyte membrane, polymer electrolyte membrane with catalyst layer, membrane electrode assembly, and polymer electrolyte fuel cell each using the same | TORAY INDUSTRIES, INC. (JP) | 2018-10-16 | — | — | US | disclosed |
| EP-3131145-B1 | POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME | TORAY INDUSTRIES (JP) | 2018-09-05 | — | — | EP | disclosed |
| US-20170125832-A1 | POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL EACH USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2017-05-04 | — | — | US | disclosed |
| EP-3131145-A1 | POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME | Toray Industries, Inc. (JP) | 2017-02-15 | — | — | EP | disclosed |
| CN-106165175-A | High molecular electrolyte composition and use its polyelectrolyte membrane, film electrode composite element and polymer electrolyte fuel cell | 东丽株式会社 | 2016-11-23 | — | — | CN | disclosed |
| US-20080091040-A1 | Optically active alkenylphosphinic acid ester and process for producing the same | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2008-04-17 | — | — | US | disclosed |
| EP-1375505-B1 | OPTICALLY ACTIVE ALKENYLPHOSPHINIC ACID ESTER AND PROCESS FOR PRODUCING THE SAME | JAPAN SCIENCE & TECH AGENCY (JP) | 2006-09-13 | — | — | EP | disclosed |
| US-20040092752-A1 | Optically active alkenylphosphinic acid esters and process for producing the same | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1375505-A1 | OPTICALLY ACTIVE ALKENYLPHOSPHINIC ACID ESTER AND PROCESS FOR PRODUCING THE SAME | Japan Science and Technology Corporation (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-6028216-A | Asymmetric syntheses and intermediates for preparing enantiomer-enriched hydroxyphosphinyl derivatives | GUILFORD PHARMACEUTICALS INC. (US) | 2000-02-22 | — | — | US | disclosed |
| WO-1999033848-A1 | PROCESS FOR PREPARING ENANTIOMER-ENRICHED HYDROXYPHOSPHINYL DERIVATIVES | GUILFORD PHARMACEUTICALS INC. (US) | 1999-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092752-A1 | Optically active alkenylphosphinic acid esters and process for producing the same | APEH, ACOX1, PHOSPHO1 | TSHR 412/4885CA2 33/4885CA4 336/4885 |
| US-20080091040-A1 | Optically active alkenylphosphinic acid ester and process for producing the same | PHOSPHO1, APEH, ACP3 | TSHR 979/4885CA2 73/4885CA4 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.