Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.43 |
| ▸ | TUBB | P07437 | 3/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339486 | 0.89 | KDM4E (0.49) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL11435411 | 0.82 | TUBB4A (0.54) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12345885 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL6931738 | 0.81 | TPMT (0.47) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL6929610 | 0.81 | HSD17B10 (0.49) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL12419331 | 0.81 | GALK1 (0.59) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL19100836 | 0.80 | CNR1 (0.47) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL29046678 | 0.80 | CYP3A4 (0.53) | KDM4EALDH1A1HPGDNPSR1POLB | |
| SCHEMBL1739400 | 0.79 | CA1 (0.54) | KDM4EALDH1A1HPGDPOLBPPARA | |
| SCHEMBL1361427 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1HPGDNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300288-A1 | Alkenyldiarylmethanes, Fused Analogs And Syntheses Thereof | PURDUE RESEARCH FOUNDATION (US) | 2008-12-04 | — | — | US | disclosed |
| WO-2007005531-A2 | ALKENYLDIARYLMETHANES, FUSED ANALOGS AND SYNTHESES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300288-A1 | Alkenyldiarylmethanes, Fused Analogs And Syntheses Thereof | POLRMT, PNP, TYMS | KDM4E 1291/4885ALDH1A1 276/4885HPGD 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.