SCHEMBL4879460

SCHEMBL4879460

C=CCCCCCCCCC(=O)OC(=O)CCCCCCCCC=C.[Zn]

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.68
LMNA P02545 2/20 0.68
MAPT P10636 3/20 0.59
ABCC4 O15439 1/20 0.59
TSHR P16473 4/20 0.44
LPAR3 Q9UBY5 2/20 0.42
LPAR2 Q9HBW0 1/20 0.42
CYP3A4 P08684 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
USP2 O75604 2/20 0.41
RECQL P46063 1/20 0.41
PTGS1 P23219 1/20 0.40
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TRPV1 Q8NER1 1/20 0.35
FAAH O00519 1/20 0.33
MGLL Q99685 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26970359 0.98 ALDH1A1 (0.70) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL1906923 0.98 ALDH1A1 (0.70) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL23200421 0.98 ALDH1A1 (0.70) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL1902663 0.98 ALDH1A1 (0.70) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL28160231 0.96 ALDH1A1 (0.68) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL26970360 0.96 ALDH1A1 (0.67) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL11685501 0.93 ALDH1A1 (0.64) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL13685469 0.91 LMNA (0.62) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL23200419 0.89 ALDH1A1 (0.57) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL28623558 0.88 ALDH1A1 (0.59) ALDH1A1LMNAMAPTABCC4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080070875-A1 Acne treatment compositions and methods of use RESOURCES OF NATURE, INC. 2008-03-20 US disclosed
US-6437002-B1 Agent for preventing and treating skin diseases SHOWA DENKO K.K. (JP) 2002-08-20 US disclosed
CN-1300215-A Preventives/remedies for skin diseases SHOWA DENKO KK (JP) 2001-06-20 CN disclosed
EP-1077066-A1 PREVENTIVES/REMEDIES FOR SKIN DISEASES Showa Denko Kabushiki Kaisha (JP) 2001-02-21 EP disclosed