SCHEMBL4879485

SCHEMBL4879485

CCOc1c(Cl)cc(Cl)c(Cl)c1B(c1c(Cl)c(Cl)cc(Cl)c1OCC)c1c(Cl)c(Cl)cc(Cl)c1OCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.39
LMNA P02545 2/20 0.39
ALDH1A1 P00352 6/20 0.38
CHUK O15111 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 1/20 0.34
POLB P06746 3/20 0.33
CYP3A4 P08684 2/20 0.33
PKM P14618 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAPK1 P28482 1/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
NPC1 O15118 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
RAB9A P51151 2/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
ABL1 P00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4889535 0.85 HTT (0.39) HTTLMNAALDH1A1CHUKCYP1A2
SCHEMBL4887314 0.78 NPC1 (0.38) ALDH1A1CHUKCYP3A4MAPK1KMT2A
SCHEMBL4889741 0.77 LMNA (0.36) HTTLMNAALDH1A1CYP1A2POLB
SCHEMBL4889766 0.73 ALDH1A1 (0.30) HTTLMNAALDH1A1MAPK1
SCHEMBL4886102 0.71 CYP3A4 (0.53) HTTLMNAALDH1A1CYP1A2POLB
SCHEMBL12681500 0.70 CYP1A2 (0.50) HTTLMNAALDH1A1CYP1A2CYP2D6
SCHEMBL4882204 0.69
SCHEMBL4878664 0.69 NQO1 (0.42) LMNAALDH1A1POLBCYP3A4MEN1
SCHEMBL4889415 0.69 CYP1A2 (0.43) HTTLMNAALDH1A1CHUKCYP1A2
SCHEMBL10068105 0.69 MAPT (0.47) HTTLMNAALDH1A1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1817318-B1 STABILIZING METHOD AND STABILIZED COMPOSITION FOR ARYL BORON COMPOUNDS NIPPON CATALYTIC CHEM IND (JP) 2013-08-28 EP disclosed
US-20080154065-A1 Stabilizing Method and Stabilized Composition for Aryl Boron Compounds NIPPON SHOKUBAI CO., LTD. (JP) 2008-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080154065-A1 Stabilizing Method and Stabilized Composition for Aryl Boron Compounds AR, AHR, BCL6 HTT 445/4885LMNA 2555/4885ALDH1A1 1928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.