Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.73 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17483924 | 0.86 | P2RX7 (0.75) | P2RX7CA2EPHX2HDAC11HDAC6 | |
| SCHEMBL3454922 | 0.84 | P2RX7 (1.00) | P2RX7CA2EPHX2 | |
| SCHEMBL14764889 | 0.82 | P2RX7 (0.73) | P2RX7CA2EPHX2 | |
| SCHEMBL19321961 | 0.78 | P2RX7 (0.63) | P2RX7CA2EPHX2HDAC11HDAC6 | |
| SCHEMBL7571579 | 0.78 | P2RX7 (0.77) | P2RX7 | |
| SCHEMBL7570497 | 0.78 | P2RX7 (0.68) | P2RX7CA2EPHX2 | |
| SCHEMBL7571999 | 0.78 | P2RX7 (0.70) | P2RX7EPHX2 | |
| SCHEMBL14160432 | 0.77 | P2RX7 (0.71) | P2RX7EPHX2 | |
| SCHEMBL11450782 | 0.76 | CNR2 (0.73) | — | |
| SCHEMBL5431054 | 0.76 | P2RX7 (0.60) | P2RX7CA2HDAC11HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064432-A1 | POLYCYCLIC MOLECULAR COMPOUNDS | THE UNIVERSITY OF SYDNEY (AU) | 2008-06-05 | — | — | WO | disclosed |
| WO-2008064432-A1 | POLYCYCLIC MOLECULAR COMPOUNDS | THE UNIVERSITY OF SYDNEY (AU) | 2008-06-05 | — | — | WO | disclosed |