Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.73 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454922 | 0.84 | P2RX7 (1.00) | P2RX7CA2EPHX2 | |
| SCHEMBL17483924 | 0.83 | P2RX7 (0.75) | P2RX7CA2EPHX2 | |
| SCHEMBL6054751 | 0.83 | P2RX7 (0.70) | P2RX7CA2MEN1KMT2A | |
| SCHEMBL4879622 | 0.82 | P2RX7 (0.73) | P2RX7CA2EPHX2 | |
| SCHEMBL13727383 | 0.80 | P2RX7 (0.58) | P2RX7MEN1KMT2AKDM4EEPHX2 | |
| SCHEMBL16872821 | 0.76 | FAAH (0.71) | MEN1KMT2AKDM4EEPHX2 | |
| SCHEMBL5431054 | 0.76 | P2RX7 (0.60) | P2RX7CA2MEN1KMT2AKDM4E | |
| SCHEMBL7569576 | 0.76 | P2RX7 (1.00) | P2RX7CA2MEN1KMT2AEPHX2 | |
| SCHEMBL19321961 | 0.75 | P2RX7 (0.63) | P2RX7CA2MEN1KMT2AEPHX2 | |
| SCHEMBL7570202 | 0.74 | P2RX7 (1.00) | P2RX7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036302-A1 | INDUCED TOLEROGENIC DENDRITIC CELLS FOR GENERATING CD8+ REGULATORY T CELLS | SELECTA BIOSCIENCES, INC. (US) | 2013-03-14 | — | — | WO | disclosed |