SCHEMBL48798

SCHEMBL48798

C=C(c1cc[c]cc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
MAPT P10636 3/20 0.40
HSD17B10 Q99714 2/20 0.40
HTT P42858 1/20 0.40
GFER P55789 1/20 0.40
GPR55 Q9Y2T6 1/20 0.40
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36
TSHR P16473 2/20 0.36
DAO P14920 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
ALDH1A1 P00352 1/20 0.36
RECQL P46063 2/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
C1S P09871 1/20 0.36
PRSS3 P35030 1/20 0.36
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL5208115 0.87 KMT2A (0.58) KMT2AMEN1MAPTHSD17B10HTT
SCHEMBL7930063 0.84 MEN1 (0.61) KMT2AMEN1MAPTHSD17B10HTT
SCHEMBL3844822 0.84 MEN1 (0.61) KMT2AMEN1MAPTHSD17B10HTT
Benzene SCHEMBL9731493 0.84 MEN1 (0.61) KMT2AMEN1MAPTHSD17B10HTT
SCHEMBL26736 0.84 MEN1 (0.61) KMT2AMEN1MAPTHSD17B10HTT
Benzene SCHEMBL28340939 0.84 MEN1 (0.61) KMT2AMEN1MAPTHSD17B10HTT
SCHEMBL9580054 0.81 MEN1 (0.58) KMT2AMEN1MAPTHSD17B10HTT
Hydrochloric Acid SCHEMBL10598447 0.81 KMT2A (0.58) KMT2AMEN1MAPTHSD17B10HTT
SCHEMBL11434494 0.81 MEN1 (0.58) KMT2AMEN1MAPTHSD17B10HTT
SCHEMBL8210944 0.81 MEN1 (0.58) KMT2AMEN1MAPTHSD17B10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107333814-A Vegetable insecticide and preparation method thereof 合肥助航生态农业科技有限公司 2017-11-10 CN claimed
CN-107079934-A Wheat insecticide and preparation method thereof 合肥助航生态农业科技有限公司 2017-08-22 CN claimed
EP-3239183-B1 MODIFIED CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION CONTAINING SAID POLYMER SUMITOMO CHEMICAL CO (JP) 2020-03-11 EP disclosed
CN-110431704-A block copolymer electrolyte for lithium battery BLUE SOLUTIONS CANADA INC 2019-11-08 CN disclosed
CN-106609039-B Polyphenyl ether resin composition and application thereof in high-frequency circuit substrate 广东生益科技股份有限公司 2019-09-13 CN disclosed
CN-110204668-A One kind is suitable for double silicon hydrogen functionalization line polymers and preparation method thereof of Si―H addition reaction chemical reaction 大连理工大学 2019-09-06 CN disclosed
CN-109790480-A The total base number promoting agent of marine diesel engine lubricating composition 路博润公司 2019-05-21 CN disclosed
US-10118973-B2 Modified conjugated diene polymer, and polymer composition containing said polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-11-06 US disclosed
CN-104045769-B Conjugated diene polymer, and the polymer composition containing the polymer 住友化学株式会社 2018-10-30 CN disclosed
CN-107001491-B Modified conjugated diene polymer and the polymer composition containing the polymer 住友化学株式会社 2018-07-06 CN disclosed
EP-2857446-B1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-03-07 EP disclosed
EP-1637550-A2 Catalytic processes for the controlled polymerization of free radically (co) polymerizable monomers and functional polymeric systems prepared thereby CARNEGIE-MELLON UNIVERSITY (US) 2006-03-22 EP disclosed
CN-1745116-A Conjugated diene polymers and copolymer blocks and process for preparing same KRATON POLYMERS US LLC (NL) 2006-03-08 CN disclosed
US-20060032390-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2006-02-16 US disclosed
EP-1621341-A2 Lithographic printing plate precursor and lithographic printing method Fuji Photo Film Co., Ltd. (JP) 2006-02-01 EP disclosed
US-20050153839-A1 Isocyanate composition, microcapsule and production method thereof, and recording material FUJI PHOTO FILM CO., LTD. 2005-07-14 US disclosed
US-6914119-B2 Heat-resistant polyether, curable polyether, and coating liquid for forming a polyether film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-05 US disclosed
US-20040091810-A1 Microcapsule, and heat-sensitive recording material and multicolor heat-sensitive recording material using the same FUJI PHOTO FILM CO., LTD. 2004-05-13 US disclosed
US-20040087760-A1 (di)aminoaroyl- or (di)aminoarylsulfonyl- endcapped polyalkylene oxide prepared by reacting the polyalkylene oxide with a (di)nitroaryl-carbonyl chloride or -sulfonyl chloride and reducing the product FUJI PHOTO FILM CO., LTD. 2004-05-06 US disclosed
US-20030060591-A1 Heat-resistant polyether, curable polyether, and coating liquid for forming a polyether film SUMITOMO CHEMICAL COMPANY, LIMITED 2003-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030060591-A1 Heat-resistant polyether, curable polyether, and coating liquid for forming a polyether film HEATR1, HSP90AA1, HEATR6 KMT2A 903/4885MEN1 4111/4885MAPT 1091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.