Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6379833 | 0.84 | NPC1 (0.55) | NPC1RAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL21104444 | 0.81 | ALDH1A1 (0.51) | NPC1RAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL7757826 | 0.80 | NPC1 (0.58) | NPC1RAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL6536489 | 0.79 | ALDH1A1 (0.56) | NPC1RAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL433221 | 0.79 | ALDH1A1 (0.56) | NPC1RAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL27908167 | 0.79 | NPC1 (0.47) | NPC1RAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL8924559 | 0.79 | ALDH1A1 (0.49) | NPC1RAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL1433300 | 0.78 | NPC1 (0.60) | NPC1RAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL20912441 | 0.78 | NPC1 (0.52) | NPC1RAB9ALMNAALDH1A1KMT2A | |
| SCHEMBL422787 | 0.77 | RAB9A (0.62) | NPC1RAB9ALMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301127-A | 6-Oxo-decahydro pyrrolo [1,2-a ] [1,5] diazocine and 6-oxo-decahydro-4H-pyrrolo [2,1-d ] [1,5] thiaazacine derivatives as modulators of STAT3 and STAT6 for the treatment of cancer and inflammatory conditions | 瑞克鲁迪克斯制药股份有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119183453-A | STAT modulators and uses thereof | 瑞克鲁迪克斯制药股份有限公司 | 2024-12-24 | — | — | CN | disclosed |
| WO-2008060268-A2 | TAILORABLE HYDROPHILIC SURFACE MODIFICATION | NORTHWESTERN UNIVERSITY (US) | 2008-05-22 | — | — | WO | disclosed |