Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 3/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 2/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4149113 | 0.79 | CNR1 (0.45) | CNR1CNR2GSK3BKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3288995 | 0.78 | KDM4E (0.48) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL4172149 | 0.73 | KDM4E (0.35) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL4183630 | 0.72 | KDM4E (0.34) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL2191820 | 0.72 | GSK3B (0.46) | CNR1CNR2GSK3BKDM4EALDH1A1 | |
| SCHEMBL4886270 | 0.70 | KDM4E (0.43) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30542771 | 0.69 | KDM4E (0.44) | CNR1CNR2KDM4EALDH1A1HPGD | |
| SCHEMBL4175956 | 0.68 | KDM4E (0.37) | GSK3BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10572613 | 0.67 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10TOP2A | |
| Trifluoroacetic Acid SCHEMBL4175924 | 0.66 | KDM4E (0.42) | GSK3BKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096829-A1 | Macrolone Compounds | GLAXO GROUP LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096829-A1 | Macrolone Compounds | MRPL21, MRPS18A, MRPL19 | CNR1 4426/4885CNR2 4739/4885GSK3B 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.