Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | MTOR | P42345 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4627149 | 0.87 | ADRB2 (0.79) | ADRB2ADRB1TDP1TSHRCYP1A2 | |
| SCHEMBL4627996 | 0.86 | ADRB2 (0.54) | ADRB2ADRB1MAPTTDP1KDM4E | |
| Colterol SCHEMBL3207818 | 0.85 | ADRB2 (0.72) | ADRB2ADRB1MAPTTDP1KDM4E | |
| Colterol SCHEMBL249585 | 0.85 | ADRB2 (0.72) | ADRB2ADRB1MAPTTDP1KDM4E | |
| Colterol SCHEMBL3220142 | 0.85 | ADRB2 (0.72) | ADRB2ADRB1MAPTTDP1KDM4E | |
| SCHEMBL4884008 | 0.83 | ADRB3 (0.59) | ADRB2ADRB1TDP1TSHRADRB3 | |
| Colterol SCHEMBL10604477 | 0.79 | ADRB2 (0.63) | ADRB2ADRB1MAPTTDP1KDM4E | |
| Colterol SCHEMBL636005 | 0.79 | PMP22 (0.71) | ADRB2ADRB1MAPTTDP1KDM4E | |
| SCHEMBL4627979 | 0.79 | ADRB2 (0.72) | ADRB2ADRB1KDM4ETSHRADRB3 | |
| SCHEMBL5337715 | 0.78 | ADRB2 (0.62) | ADRB2ADRB1MAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | SOSEI R&D LTD. (GB) | 2008-12-11 | — | — | US | claimed |
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | SOSEI R&D LTD. (GB) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306162-A1 | Treatment of Inflammatory Disorders and Pain | HRH3, OPRL1, HRH2 | ADRB2 131/4885ADRB1 198/4885MAPT 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.