Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.50 |
| ▸ | MTOR | P42345 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4880117 | 0.78 | ADRB2 (0.61) | ADRB2ADRB1TDP1MAPTMEN1 | |
| Colterol SCHEMBL249585 | 0.76 | ADRB2 (0.72) | ADRB2ADRB1TDP1MAPTMEN1 | |
| Colterol SCHEMBL3207818 | 0.76 | ADRB2 (0.72) | ADRB2ADRB1TDP1MAPTMEN1 | |
| Colterol SCHEMBL3220142 | 0.76 | ADRB2 (0.72) | ADRB2ADRB1TDP1MAPTMEN1 | |
| SCHEMBL7149089 | 0.74 | ADRB2 (0.74) | ADRB2ADRB1TDP1MAPTMEN1 | |
| SCHEMBL11807907 | 0.74 | ADRB2 (0.74) | ADRB2ADRB1TDP1MAPTMEN1 | |
| SCHEMBL7149088 | 0.74 | ADRB2 (0.74) | ADRB2ADRB1TDP1MAPTMEN1 | |
| SCHEMBL30892159 | 0.73 | ADRB3 (0.64) | ADRB2ADRB1TDP1MAPTMEN1 | |
| SCHEMBL22551319 | 0.73 | ADRB3 (0.64) | ADRB2ADRB1TDP1MAPTMEN1 | |
| SCHEMBL11878876 | 0.72 | ADRB2 (0.72) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7232659-B1 | Multiplex analysis for high throughput discrimination of GPCR agonists and antagonists | STC.UNM (US) | 2007-06-19 | — | — | US | disclosed |
| EP-0835233-B1 | COMPOSITION AND METHOD FOR STABILIZING RADIOLABELED ORGANIC COMPOUNDS | NEN LIFE SCIENCE PROD INC (US) | 2001-12-05 | — | — | EP | disclosed |
| US-5843396-A | Method for stabilizing radiolabeled organic compounds by adding a separate stabilizing compound | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0835233-A1 | COMPOSITION AND METHOD FOR STABILIZING RADIOLABELED ORGANIC COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |
| US-5738836-A | Composition for stabilizing radiolabeled organic compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1997001520-A1 | COMPOSITION AND METHOD FOR STABILIZING RADIOLABELED ORGANIC COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-16 | — | — | WO | disclosed |
| US-4411881-A | Composition and method for stabilizing radiolabeled compounds using thiocarbonylated diethylenetriamines | NEW ENGLAND NUCLEAR CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |