Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626035 | 1.00 | MME (0.54) | MMENPSR1CYP1A2NAALAD2MMP2 | |
| SCHEMBL5560323 | 1.00 | MME (0.54) | MMENPSR1CYP1A2NAALAD2MMP2 | |
| SCHEMBL1081373 | 0.86 | FOLH1 (0.54) | MMENAALAD2ACEL3MBTL1FOLH1 | |
| SCHEMBL31533361 | 0.86 | FOLH1 (0.54) | MMENAALAD2ACEL3MBTL1FOLH1 | |
| SCHEMBL31533362 | 0.86 | FOLH1 (0.54) | MMENAALAD2ACEL3MBTL1FOLH1 | |
| SCHEMBL1081372 | 0.86 | FOLH1 (0.54) | MMENAALAD2ACEL3MBTL1FOLH1 | |
| SCHEMBL12207239 | 0.85 | MME (0.57) | MMENPSR1CYP1A2NAALAD2MMP2 | |
| SCHEMBL7596254 | 0.85 | MME (0.57) | MMENPSR1CYP1A2NAALAD2MMP2 | |
| SCHEMBL23925862 | 0.83 | MME (0.56) | MMENPSR1CYP1A2NAALAD2MMP2 | |
| SCHEMBL73955 | 0.83 | MME (0.56) | MMENPSR1CYP1A2NAALAD2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931707-A1 | RAT TRPM7 POLYNUCLEOTIDE AND ENCODED PROTEIN | Wyeth a Corporation of the State of Delaware (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007041687-A1 | RAT TRPM7 POLYNUCLEOTIDE AND ENCODED PROTEIN | WYETH (US) | 2007-04-12 | — | — | WO | disclosed |