Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | XIAP | P98170 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12207239 | 1.00 | MME (0.57) | MMENPSR1CYP1A2NAALAD2FOLH1 | |
| SCHEMBL995917 | 0.91 | NPSR1 (0.55) | MMENPSR1CYP1A2NAALAD2FOLH1 | |
| SCHEMBL27699635 | 0.91 | MME (0.56) | MMENPSR1NAALAD2ACECPA1 | |
| SCHEMBL27699637 | 0.91 | MME (0.56) | MMENPSR1NAALAD2ACECPA1 | |
| SCHEMBL30673629 | 0.89 | MME (0.51) | MMENPSR1CYP1A2NAALAD2FOLH1 | |
| SCHEMBL31688792 | 0.89 | SIGMAR1 (0.59) | MMENPSR1CYP1A2NAALAD2MMP2 | |
| SCHEMBL3343350 | 0.89 | SIGMAR1 (0.59) | MMENPSR1CYP1A2NAALAD2MMP2 | |
| SCHEMBL29091477 | 0.89 | MME (0.51) | MMENPSR1CYP1A2NAALAD2FOLH1 | |
| SCHEMBL547203 | 0.89 | NAALAD2 (0.60) | MMENPSR1CYP1A2NAALAD2ACE | |
| SCHEMBL661567 | 0.89 | SIGMAR1 (0.59) | MMENPSR1CYP1A2NAALAD2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061956-B1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO SPA (IT) | 2002-12-11 | — | — | EP | disclosed |
| US-6337064-B1 | USED AS CONTRAST AGENT IN MAGNETIC RESONANCE IMAGING, MEDICAL DIAGNOSIS | DIBRA S.P.A. (IT) | 2002-01-08 | — | — | US | disclosed |