SCHEMBL73955

SCHEMBL73955

O=C(O)[C@H](Cc1ccccc1)NCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.56
ALDH1A1 P00352 1/20 0.55
NPSR1 Q6W5P4 1/20 0.54
MEP1B Q16820 2/20 0.54
PSMB5 P28074 1/20 0.54
CYP1A2 P05177 1/20 0.53
SIGMAR1 Q99720 1/20 0.53
NAALAD2 Q9Y3Q0 2/20 0.53
FOLH1 Q04609 1/20 0.51
ANPEP P15144 1/20 0.51
MMP2 P08253 1/20 0.51
MMP9 P14780 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11581853 1.00 MME (0.56) MMEALDH1A1NPSR1MEP1BPSMB5
SCHEMBL497336 1.00 MME (0.56) MMEALDH1A1NPSR1MEP1BPSMB5
Hydrochloric Acid SCHEMBL1027766 0.98 MME (0.54) MMEALDH1A1NPSR1MEP1BPSMB5
Hydrochloric Acid SCHEMBL7362927 0.98 MME (0.54) MMEALDH1A1NPSR1MEP1BPSMB5
SCHEMBL17915462 0.93 MME (0.61) MMEALDH1A1MMP2MMP9
SCHEMBL121370 0.92 MME (0.58) MMEALDH1A1PSMB5NAALAD2FOLH1
SCHEMBL121371 0.92 MME (0.58) MMEALDH1A1PSMB5NAALAD2FOLH1
Benzophenone SCHEMBL9490253 0.92 MEP1B (0.55) MMEALDH1A1NPSR1MEP1BPSMB5
SCHEMBL11346818 0.92 MME (0.58) MMEALDH1A1PSMB5NAALAD2FOLH1
Benzophenone SCHEMBL9490249 0.92 MEP1B (0.55) MMEALDH1A1NPSR1MEP1BPSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 772 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3229612-B1 USE OF FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2024-06-26 EP claimed
US-20240197666-A1 DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) K-GEN THERAPEUTICS, INC. (US) 2024-06-20 US claimed
WO-2024064391-A2 USE OF PROTEIN KINASE C (PKC) ACTIVATING COMPOUNDS AS AN ADJUVANT K-GEN THERAPEUTICS, INC. (US) 2024-03-28 WO claimed
EP-4313095-A1 DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) K-Gen Therapeutics, Inc. (US) 2024-02-07 EP claimed
CN-117098544-A Diterpenoid compounds acting on Protein Kinase C (PKC) K-GEN治疗股份有限公司 2023-11-21 CN claimed
US-20220411362-A1 DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) K-GEN THERAPEUTICS, INC. 2022-12-29 US claimed
WO-2022204327-A1 DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) K-GEN, INC. (US) 2022-09-29 WO claimed
EP-4041268-A1 DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) K-Gen, Inc. (US) 2022-08-17 EP claimed
CN-114786697-A Diterpenoids acting on Protein Kinase C (PKC) K-GEN股份有限公司 2022-07-22 CN claimed
CN-114533890-A Preparation method and product of sorafenib liver cancer targeting micelle 平顶山学院 2022-05-27 CN claimed
EP-2413711-A1 DIPEPTIDE AS FEEDSTUFF ADDITIVE Evonik Degussa GmbH (DE) 2012-02-08 EP claimed
WO-2011147881-A2 CYCLIC DIPEPTIDES AS FEEDSTUFF ADDITIVES EVONIK DEGUSSA GMBH (DE) 2011-12-01 WO claimed
WO-2010112365-A1 DIPEPTIDE AS FEEDSTUFF ADDITIVE EVONIK DEGUSSA GMBH (DE) 2010-10-07 WO claimed
US-20100029646-A1 PRODRUGS OF DIPHENYL OX-INDOL-2-ONE COMPOUNDS TOPO TARGET A/S (DK) 2010-02-04 US claimed
EP-1689426-B1 PHARMACEUTICAL FORMULATIONS FOR THE SUSTAINED RELEASE OF INTERFERONS AND THERAPEUTIC APPLICATIONS THEREOF FLAMEL TECH SA (FR) 2009-12-30 EP claimed
EP-1689425-B1 PHARMACEUTICAL FORMULATIONS FOR THE SUSTAINED RELEASE OF ONE OR MORE ACTIVE PRINCIPLES AND THERAPEUTIC APPLICATIONS THEREOF FLAMEL TECHNOLOGIE SA (FR) 2009-12-09 EP claimed
EP-1567578-B1 POLYAMINO ACIDS FUNCTIONALIZED BY AT LEAST ONE (OLIGO)AMINO ACID GROUP AND THERAPEUTIC USES FLAMEL TECH SA (FR) 2008-06-25 EP claimed
US-20070010652-A1 Polyamino acids functionalised with at least one hydrophobic group and applications thereof particularly therapeutic applications STEPHANIE ANGOT, OLIVIER BREYNE, AND YOU-PING CHAN 2007-01-11 US claimed
EP-1017358-B1 REDUCTION OF HAIR GROWTH GILLETTE CO (US) 2004-08-11 EP claimed
US-5939458-A APPLYING AN INHIBITOR OF AMINOACYL-TRNA SYNTHETASE TO THE SKIN GILLETTE COMPANY, THE 1999-08-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220411362-A1 DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) PRKCA, PRKCH, PRKCB MME 4621/4885ALDH1A1 4294/4885NPSR1 3586/4885
US-20100029646-A1 PRODRUGS OF DIPHENYL OX-INDOL-2-ONE COMPOUNDS IDO1, IDO2, TDO2 MME 2585/4885ALDH1A1 167/4885NPSR1 1053/4885
US-20240197666-A1 DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) PRKCA, PRKCB, PRKCI MME 4709/4885ALDH1A1 4336/4885NPSR1 4039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.